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partial cut A harvest method in which portions of a stand of timber are cut during a number of entries over time. Precommercial thinning operations are not considered partial cuts.
(05 Dec 1998)
rose-cut Cut flat on the reverse, and with a convex face formed of triangular facets in rows; said of diamonds and other precious stones. See Rose diamond, under Rose. Cf. Brilliant.
Source: Websters Dictionary
(01 Mar 1998)
cross-cut bur A bur with blades located at right angles to its long axis.
(05 Mar 2000)
cut In molecular biology, a hydrolytic cleavage of two opposing phosphodiester bonds in a double-stranded nucleic acid.
Compare: nick.
(05 Mar 2000)
bearing down Expulsive effort of a parturient woman in the second stage of labour.
(05 Mar 2000)
bearing-down pain A uterine contraction accompanied by straining and tenesmus; usually appearing in the second stage of labour.
(05 Mar 2000)
reflex, let down The let down reflex of the mother is an involuntary reflex during breastfeeding which causes the milk to flow freely.
(12 Dec 1998)
milk let-down reflex Release of milk from the breast following tactile stimulation of the nipple; the afferent path is postulated to exist from the nipple to the hypothalamus; the efferent limb is represented by the neurohypophysial release of oxytocin into the systemic circulation; contraction of myoepithelial elements within the breast, caused by oxytocin, moves milk into the collecting ducts and toward the nipple.
Synonym: let-down reflex, milk let-down reflex.
(05 Mar 2000)
cone down To narrow a beam of X-rays to a region of interest using a collimator or cone; colloq., to delimit one's attention or activities.
(05 Mar 2000)
head-down tilt Posture while lying with the head lower than the rest of the body. Extended time in this position is associated with temporary physiologic disturbances.
(12 Dec 1998)
syndrome, down A common disorder due to a chromosome abnormality and specfically due to an extra chromosome number 21 (trisomy 21). Down syndrome includes mental retardation, a characteristic face, and multiple malformations. It is associated with a major risk for heart problems, a lesser risk of duodenal atresia (part of the intestines not developed), and a minor but still significant risk of acute leukaemia. The name down syndrome comes from the 19th century english doctor langdon down, a misnomer since he was curiously enough not the first person to describe the condition and, in great error, attributed the condition to a reversion to the mongoloid race. Hence, the old name mongolism, now considered slang.
(12 Dec 1998)
down <dermatology, zoology> Fine, soft feathers, soft, fine hair.
(04 Mar 1998)
Down, John Langdon <person> English physician, 1828-1896.
See: Down's syndrome.
(05 Mar 2000)
down promoter mutation <molecular biology> A mutation (a change in base pair sequence) in a promoter region, this results in lower gene expression (less transcription of the gene occurs).
(09 Oct 1997)
down-regulation <physiology> Development of a refractory or tolerant state consequent upon repeated administration of a pharmacologically or physiologically active substance.
It is the process that decreases ligand and receptor interactions or reduces the responsiveness of a cell to a stimulus following first exposure.
This is often accompanied by an initial decrease in affinity of receptors for the agent and a subsequent reduction in the number of available receptors expressed on the surface which can result from internalisation of the ligand:receptor complex or from decreased expression of the receptor.
Classically the concept referred to hormone receptors but contemporary usage includes other cell surface receptors.
(03 Jul 1999)
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