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creatine <biochemistry> A compound which is made by the body and is used to store energy in the form of phosphate molecules.
When phosphate molecules are attached to it, it is called creatine phosphate and is capable of donating phosphate to ADP in order to make ATP. (ATP is the molecule which is converted into ADP with a release of energy that the body then uses.)
(09 Oct 1997)
creatine kinase <enzyme> Dimeric enzyme (82 kD) that catalyses the formation of ATP from ADP and creatine phosphate in muscle.
Acronym: CK
(28 May 1998)
creatine kinase isoenzymes <enzyme> Three isoenzymes of creatine kinase have been identified in human tissues: mm from skeletal muscle, mb from myocardial tissue and bb from nervous tissue. Plasma from healthy humans contains mm almost exclusively. Elevated mb creatine kinase activity is a possible indicator of myocardial injury.
Registry number: EC 2.7.3.-
(12 Dec 1998)
creatine phosphate <biochemistry> Storage compound of vertebrate muscle.
See: creatine kinase.
(18 Nov 1997)
creatine phosphokinase <enzyme> An enzyme that is contained in skeletal muscle, smooth muscle and cardiac muscle.
Creatine phosphokinase is released into the bloodstream in increased quantities if muscle in injured. Creatine phosphokinase can be fractionated so that specific measurements can be made for blood levels of creatine phosphokinase that comes exclusively from damaged heart muscle. This makes it an important test for the laboratory diagnosis of heart attack.
Acronym: CPK
(28 May 1998)
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