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corticosteroid-induced glaucoma <ophthalmology> Glaucoma caused by a hereditary predisposition in which local instillation of eyedrops containing corticosteroid causes increased intraocular pressure.
(05 Mar 2000)
corticosteroid <drug, endocrinology, pharmacology> Any of the steroids elaborated by the adrenal cortex (excluding the sex hormones of adrenal origin) in response to the release of adrenocorticotrophin or adrenocorticotropic hormone (ACTH) by the pituitary gland, to any of the synthetic equivalents of these steroids or to angiotensin II.
They are divided, according to their predominant biological activity, into three major groups: glucocorticoids (e.g. Cortisol, cortisone), chiefly influencing carbohydrate, fat and protein metabolism, mineralocorticoids (for example aldosterone), affecting the regulation of electrolyte and water balance and C19 androgens.
Some corticosteroids exhibit both types of activity in varying degrees and others exert only one type of effect.
The corticosteroids are used clinically for hormonal replacement therapy, for suppression of ACTH secretion by the anterior pituitary, as antineoplastic, antiallergic and anti-inflammatory agents and to suppress the immune response.
Synonym: adrenocortical hormone, corticoid.
(13 Nov 1997)
corticosteroid-binding globulin <chemical> Chemical name: Transcortins
(12 Dec 1998)
corticosteroid-binding protein <chemical> Chemical name: Transcortins
(12 Dec 1998)
corticosteroid cream <drug, pharmacology> This is a large group of trade name medications that contain an anti-inflammatory steroid. These cream based medications all contain either hydrocortisone in varying concentrations or a synthetic steroid with much greater potency. This type of medications is useful in the treatment of a large number of inflammatory rashes. Caution: higher potency creams can cause side effects.
Examples include hydrocortisone, dexamethasone, flunisolide, fluocinonide, fluprednisolone, Aclovate, Alphatrex, Aristocort, Betatrex, Cortone, Diprolene, Valisone, Halog, Hytone, Kenalog, Lidex, Lotrisone, Synalar, Synemol, Topicort, Vytone, Westcort and Vioform.
(27 Sep 1997)
corticosteroid-induced acne The exacerbation of acne after corticosteroid use is a common drug reaction seen in adolescents. Lessening the dose of the corticosteroid will often diminish this effect.
(27 Sep 1997)
corticosteroid-induced striae <dermatology> High-dose glucocorticoid therapy causes atrophy of the skin and a failure of the normal regenerative process. Purple striae often develop over the individual's trunk or thighs. The colour fades when the drug is stopped, but the dermal atrophy remains.
(27 Sep 1997)
corticosteroid side-chain-isomerase <enzyme> Converts 11-deoxycorticosterone to 20-hydroxy-3-oxypregn-4-en-21-al; also acts as an epimerase at c-20
Registry number: EC 5.3.1.21
Synonym: corticosteroid side chain isomerase, ccsci
(26 Jun 1999)
absolute glaucoma The final stage of blindness in glaucoma.
(05 Mar 2000)
acute angle closure glaucoma <ophthalmology> An increase in pressure within the anterior chamber of the eye. There are two forms of glaucoma: acute angle closure and open angle glaucoma.
(27 Sep 1997)
acute glaucoma <ophthalmology> A sudden blockage of the normal fluid circulation within the eyeball resulting in increased intraocular pressure. Increased pressure within the eyeball can cause damage to the optic nerve and blindness.
Symptom include severe eye or facial pain, nausea, vomiting, decreased vision, blurred vision and seeing halos around objects. The eye appears red with a steamy cornea and a fixed (nonreactive) dilated pupil. Treatment is emergent with medications to lower the pressure within the eye.
(27 Sep 1997)
alpha-chymotrypsin-induced glaucoma Transient secondary glaucoma following the use of alpha-chymotrypsin in cataract extraction.
(05 Mar 2000)
angle closure glaucoma <ophthalmology> Primary glaucoma in which contact of the iris with the peripheral cornea excludes aqueous humor from the trabecular drainage meshwork causing a sudden blockage of the normal fluid circulation within the eyeball resulting in increased intraocular pressure. Increased pressure within the eyeball can cause damage to the optic nerve and blindness.
Symptoms include severe eye or facial pain, nausea, vomiting, decreased vision, blurred vision and seeing halos around objects. The eye appears red with a steamy cornea and a fixed (nonreactive) dilated pupil. Treatment is emergent with medications to lower the pressure within the eye.
Synonym: acute glaucoma, closed-angle glaucoma, narrow-angle glaucoma.
(14 Aug 2000)
aphakic glaucoma Glaucoma following cataract removal.
(05 Mar 2000)
capsular glaucoma Glaucoma occurring in association with widespread deposition of cellular organelles on the lens capsule, ocular blood vessels, iris, and ciliary body.
See: pseudoexfoliation of lens capsule.
(05 Mar 2000)
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