| core | 1. The central mass of necrotic tissue in a boil. 2. A metal casting, usually with a post in the canal of a tooth root, designed to retain an artificial crown. 3. A sectional record, usually of plaster of Paris or one of its derivatives, of the relationships of parts, such as teeth, metallic restorations, or copings. Origin: L. Cor, heart 4. The pupil (of the eye). Origin: G. Kore, pupil (05 Mar 2000) |
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| core biopsy | Removal (with a large needle) of a piece of a lump. The piece is sent to the lab to see if the lump is benign or malignant. (09 Oct 1997) |
| core I protein, ubiquinol-cytochrome c reductase | <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source Synonym: core I protein, uccreductase (26 Jun 1999) |
| core II protein, ubiquinol-cytochrome c reductase | <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source Synonym: core II protein, uccreductase (26 Jun 1999) |
| core particle | The group of eight histones (protein molecules which act like spools for DNA to wrap around so that it can be compacted to fit within the nucleus) in the middle of a nucleosome (which is the histone core particle plus the small segment of DNA wrapped around it). (09 Oct 1997) |
| core plasma | <radiobiology> Hot plasma at the centre of a fusion reactor, distinguished from edge plasma and scrape-off layer (SOL). The core plasma does not directly feel the effects of the divertor or limiter in the way the edge plasma does. (09 Oct 1997) |
| core pneumonia | A form of pneumonia in which exudation is confined for a time to the central portion of a lobe or the hilar region. Synonym: core pneumonia. (05 Mar 2000) |
| corectopia | Eccentric location of the pupil so that it is not in the centre of the iris. Origin: G. Kore, pupil, + ektopos, out of place (05 Mar 2000) |
| corelysis | A rarely used term for freeing of adhesions between lens capsule and the iris. Origin: G. Kore, pupil, + lysis, a loosening (05 Mar 2000) |
| coremium | A sheaf-like tuft of conidiophores. Origin: G. Korema, filth, refuse (05 Mar 2000) |
| coreoplasty | The procedure to correct a misshapen, miotic, or occluded pupil. Origin: G. Kore, pupil, + plasso, to form (05 Mar 2000) |
| corepexy | A suturing of the iris to modify the shape or size of the pupil. Purse-string corepexy, a "pajama-string suture" threaded along the pupillary margin and tied down to make a large pupil small. (05 Mar 2000) |
| corepraxy | A procedure designed to widen a small pupil. Origin: G. Kore, pupil, + praxis, action Laser corepraxy, the iris stroma is heated with a laser and the resultant contracture of iris tissue widens the pupil. Mechanical corepraxy, a procedure that lodges the pupillary margin in the groove of a device which, when widened, stretches the pupillary edge to make the pupil larger. (05 Mar 2000) |
| corepressor | An effector molecule which can bind to a repressor molecule, so that together the effector repressor complex can stop transcription of a gene. (09 Oct 1997) |
| Corey | R.B., U.S. Chemist, 1897-1971. See: Pauling-Corey helix. (05 Mar 2000) |
| atomic core | The nucleus plus the nonvalence electrons. (05 Mar 2000) |
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| viral core proteins | Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the nucleocapsid. (12 Dec 1998) |
| central core disease | A congenital myopathy characterised by hypotonia, delay of motor development in infancy, and nonprogressive or slowly progressive muscle weakness; on biopsy the central core of muscle fibres stains abnormally, myofibrils are abnormally compact, and there is virtual absence of mitochondria and sarcoplasmic reticulum; histochemically, the cores are devoid of oxidative enzyme, phosphorylase, and ATPase activity; autosomal dominant inheritance, often subclinical. (05 Mar 2000) |
| central core disease of muscle | <neurology> One of the conditions that produces floppy baby syndrome. It causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). The disease is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). Inheritance: autosomal dominant. (12 Dec 1998) |
| central transactional core | The reticular activating system of the brain. (05 Mar 2000) |
| muscle, central core disease of | One of the conditions that produces 'floppy baby' syndrome. Ccd causes hypotonia (inadequately toned muscles characterised by floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type i muscle fibres). Ccd is inherited as a dominant trait. The ccd gene is on chromosome 19 (and involves ryanodine receptor-1). (12 Dec 1998) |
| post and core technique | Use of a metal casting, usually with a post in the pulp or root canal, designed to support and retain an artificial crown. (12 Dec 1998) |
| hepatitis B core antigen | <virology> (HBcAb, HBcAg), the antigen found in the core of the Dane particle (which is the complete virus) and also in hepatocyte nuclei in hepatitis B infections. (05 Mar 2000) |
| HIV core protein p24 | A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by elisa and western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines. (12 Dec 1998) |
| disease, central core, of muscle | <anatomy> One of the conditions that produces 'floppy baby' syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). CCD is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). (12 Dec 1998) |