| coproporphyrinogen | See: porphyrinogens. Coproporphyrinogen oxidase, an enzyme that catalyses a step in porphyrin biosynthesis, reacting coproporphyrinogen-III and O2 to form protoporphyrinogen-IX and 2CO2. A deficiency of this enzyme will result in hereditary coproporphyria. (05 Mar 2000) |
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| coproporphyrinogen oxidase | <enzyme> One of the enzymes active in haem biosynthesis. It catalyses the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen III by the conversion of two propionic acid groups to two vinyl groups. It can act under both aerobic and anaerobic conditions. Chemical name: Coproporphyrinogen:oxygen oxidoreductase (decarboxylating) Registry number: EC 1.3.3.3 (12 Dec 1998) |
| coproporphyrinogens | Porphyrinogens which are intermediates in the haem biosynthesis. They have four methyl and four propionic acid side chains attached to the pyrrole rings. Coproporphyrinogens I and III are formed in the presence of uroporphyrinogen decarboxylase from the corresponding uroporphyrinogen. They can yield coproporphyrins by autooxidation or protoporphyrin by oxidative decarboxylation. (12 Dec 1998) |