| RCS | Recombinant Congenic Strain |
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| congenic | <cell biology> Organisms that differ in genotype at (ideally) one specified locus. Strictly speaking these are conisogenics. Thus one homozygous strain can be spoken of as being congenic to another. (18 Nov 1997) |
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| congenic strain | An inbred strain of animals produced by continued crossing of a gene of one line onto another inbred (isogenic) line. (05 Mar 2000) |
| congenic |
pertaining to two inbred strains of animals that are genetically identical except at a single locus or a few specified loci so that their known genetic differences are expressed in the same “genetic background.” A congenic strain is produced by outbreeding a strain and then eliminating the background genes by many generations of backcrosses while maintaining the desired genetic differences by selection of progeny. Called also coisogenic.
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