| competitive inhibition | <chemistry> Inhibitor that occupies the active site of an enzyme or the binding site of a receptor and prevents the normal substrate or ligand from binding. at sufficiently high concentration of the normal ligand inhibition is lost: the Km is altered by the competitive inhibitor, but the Vmax remains the same. (05 Jan 1998) |
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| competitive antagonist | An antimetabolite. (05 Mar 2000) |
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| competitive behaviour | The direct struggle between individuals for environmental necessities or for a common goal. (12 Dec 1998) |
| competitive bidding | Pricing statements presented by more than one party for the purpose of securing a contract. (12 Dec 1998) |
| competitive binding assay | General term for an assay in which a binder competes for labelled versus unlabelled ligand; following separation of free and bound ligand, the ligand (the analyte assayed) is quantitated by relating bound and unbound ratios to known standards. See: enzyme-linked immunosorbent assay, radioreceptor assay, immunoassay, enzyme-multiplied immunoassay technique, radioimmunoassay. Synonym: displacement analysis, saturation analysis. (05 Mar 2000) |
| competitive medical plans | Alternative health care delivery mechanisms, such as preferred provider organizations or other health insurance services or prepaid plans (other than health maintenance organizations), that meet medicare qualifications for a risk-sharing contract. (12 Dec 1998) |
| allogeneic inhibition | Inhibition or injury to allogeneic cells that occurs when lymphocytes are mixed and cultured with other cells of different genotypes in vitro. (05 Mar 2000) |
| macrophage inhibition factor | <cytokine> A group of lymphokines (including a 14 kD glycoprotein) produced by activated T lymphocytes that reduces macrophage mobility and probably increases macrophage macrophage adhesion. (18 Nov 1997) |
| macrophage migration inhibition test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| reactive inhibition | Tendency toward a lessened strength of response due to practice or activity. It is independent of the effect of reward and is a direct function of time interval since the last response and the number of preceding responses. (12 Dec 1998) |
| reciprocal inhibition | Contraction in a muscle is accompanied by a loss of tone or by relaxation in the antagonistic muscle. Synonym: reciprocal inhibition. (05 Mar 2000) |
| reflex inhibition | A situation in which sensory stimuli decrease reflex activity. (05 Mar 2000) |
| cell migration inhibition | Phenomenon of cell-mediated immunity measured by in vitro inhibition of the migration or phagocytosis of antigen-stimulated leukocytes or macrophages. Specific assays have been developed to estimate levels of migration-inhibitory factor, immune reactivity against tumour-associated antigens, and immunosuppressive effects of infectious microorganisms. (12 Dec 1998) |
| central inhibition | <physiology> Suppression or diminution of outgoing impulses from a reflex centre. (05 Mar 2000) |
| residual inhibition | The inhibition or suppression of tinnitus by use of a sound-generating device (residual inhibitor) which masks the sounds of tinnitus and produces a residual sound-inhibiting effect when the device is turned off. (05 Mar 2000) |
| retroactive inhibition | The partial or complete obliteration of memory by a more recent event, particularly new learning. Compare: proactive inhibition. (05 Mar 2000) |