| comedo | <pathology> A plug of keratin and sebum within the dilated orifice of a hair follicle, frequently containing the bacteria Propionibacterium acnes, Staphylococcus albus and Pityrosporon ovale, also called blackhead. See: acne. (18 Nov 1997) |
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| comedocarcinoma | <tumour> Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells may be expressed from the ducts. (05 Mar 2000) |
| comedogenic | Tending to promote the formation of comedones. Synonym: acnegenic. Origin: comedo + G. Genesis, production (05 Mar 2000) |
| comedonecrosis | A type of necrosis occurring with glands in which there is central luminal inflam-mation with devitalised cells, usually occurring in the breast in intraductal carcinoma. Origin: comedo + necrosis (05 Mar 2000) |
| closed comedo | A comedo with a narrow or obstructed opening on the skin surface; closed comedo's may rupture, producing a low-grade dermal inflammatory reaction. Synonym: whitehead. (05 Mar 2000) |
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| open comedo | A comedo with a wide opening on the skin surface capped with a melanin-containing blackened mass of epithelial debris. Synonym: blackhead. (05 Mar 2000) |