| combining site | <biochemistry, immunology> Any region of a molecule that binds or reacts with a given compound. Especially of the region of immunoglobulin that combines with the determinant of an appropriate antigen. (09 Jan 1998) |
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| combining weight | The weight in grams of an element that combines with or replaces 1 gram of hydrogen, the atomic or molecular weight in grams of an atom or group of atoms involved in a chemical reaction divided by the number of electrons donated, taken up, or shared by the atom or group of atoms in the course of that reaction, the weight of a substance contained in 1 liter of 1 normal solution; a variant of. Synonym: combining weight, equivalent weight. (05 Mar 2000) |
| antibody combining site | <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope). Also used of the site on a ligand molecule to which a cell surface receptor binds. (18 Nov 1997) |
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| antigen-combining site | See: paratope. (05 Mar 2000) |