| ¿µ¹® | collagen | ÇÑ±Û | ¾Æ±³Áú, ÄݶóÁ¨ |
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| ¼³¸í | °áÇÕÁ¶Á÷ÀÇ ¼¼Æ÷ÀÇ ±âÁúÀ» ±¸¼ºÇÏ´Â ÁÖ¿äÇÑ ¼¶À¯¼º ´Ü¹éÁúÀÌ´Ù. »ç¶÷¿¡¼´Â »ýüÀÇ Àüü´Ü¹éÁúÀÇ ¾à 30%¸¦ Â÷ÁöÇÑ´Ù. ºÐÀÚ·® 30~35¸¸, ±¸¼º¾Æ¹Ì³ë»êÀ¸·Î¼ ±Û¸®½Å°ú ÇÁ·Ñ¸°ÀÌ ¸¹°í ÇÔÀ¯¾Æ¹Ì³ë»êÀÌ Àû´Ù. ƯÀ¯ ¾Æ¹Ì³ë»êÀ¸·Î¼ È÷µå·Ï½ÃÇÁ·Ñ¸°°ú È÷µå·Ï½Ã¸®½ÅÀ» Æ÷ÇÔÇÑ Æ¯ÀÌÇÑ ¾Æ¹Ì³ë»ê Á¶¼ºÀ» ³ªÅ¸³»¸ç ºÐÀÚ³»¿¡ ¿¬¼ÓµÇ´Â Gly-Pro-XÀÇ µÇÇ®ÀÌ ±¸Á¶¸¦ °®´Â´Ù. ºÐÀÚ±¸Á¶ÀÇ ´Ù¸§¿¡ µû¶ó I~VIIIÇüÀ¸·Î ºÐ·ùµÇÁö¸¸ ¿äÁò ´õ¿í »õ·Î¿î ºÐÀÚÇüÀÌ º¸°íµÇ°í ÀÖ´Ù. Á¶Á÷ÇüÅÂÀÇ °ñ°Ý±¸Á¶ÀÇ À¯Áö, °¢Á¾¼¼Æ÷ÀÇ ÈíÂø, ¼¼Æ÷ÀÇ ºÐÈ-Áõ½Ä µî¿¡ °ü¿©ÇÏ´Â ¿Ü¿¡ °æÁ¶Á÷ÀÇ ¼®È¸È¿¡ ÀÖ¾î¼ÀÇ ¹ÙÅÁÁú·Î¼ Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù. |
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| ¿µ¹® | obsessive-compulsive disorder | ÇÑ±Û | °¹Ú¹ÝÀÀ¼º Àå¾Ö |
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| ¼³¸í | °¹Ú»ç°í(obsession)Àº ¹Ýº¹µÇ´Â »ç°í¸¦ ¸»Çϸç, °¹ÚÇàÀ§(compulsion)´Â ¹Ýº¹µÇ´Â ÇൿÀ» ¸»ÇÑ´Ù. Áï ¹Ýº¹µÇ´Â »ç°í¿¡ µû¶ó ¹Ýº¹ÀûÀÎ ÇൿÀ» ¼öÇàÇÏ´Â Àå¾Ö¸¦ ¸»ÇÑ´Ù. À̶§ ¹Ýº¹ÀûÀÎ »ç°í´Â ÀÌ·ÐÀûÀ¸·Î ÀÌÇØµÇÁö ¾Ê´Â °æ¿ì°¡ ¸¹°í, º»Àεµ ÀÌ·± »ç°í°¡ ÀÌÇØµÇÁö ¾Ê´Â´Ù´Â »ç½ÇÀ» ¾Ë°í °íÄ¡·Á°í ÇÏÁö¸¸, Àß µÇÁö ¾Ê´Â´Ù. ¶ÇÇÑ °è¼ÓÀûÀ¸·Î ÀÌ·± »ç°í¿¡ µû¸¥ ¹Ýº¹ÀûÀÎ ÇൿÀ» Çϸç, ÀÌ·± ÇൿÀ» ¼öÇàÄ¡ ¾ÊÀ» ½Ã, º»ÀÎÀÇ ÀÇÁö¿Í ¹«°üÇÏ°Ô ¸÷½Ã ºÒ¾ÈÇØÇϰí, ÃÊÁ¶ÇØÇÑ´Ù. |
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| ¿µ¹® | panic disorder | ÇÑ±Û | °øÈ²Àå¾Ö |
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| ¼³¸í | ¹Ýº¹µÇ´Â °øÈ²¹ßÀÛ(panic attack: °©ÀÛ½º·± °øÆ÷»óÅÂÀÇ ¹ßº´)°ú ½Å°æ°ú¹ÎÀ» ³ªÅ¸³»´Â °æ¿ì¸¦ ¸»ÇÔ. °øÈ²¹ßÀÛÀº ´Üµ¶À¸·Î ÀϾ±âº¸´Ù´Â ¿À·£ ±äÀå»óÅ¿¡¼ ÁÖ±âÀûÀ¸·Î ÀϾ´Â Çö»óÀ¸·Î º¸ÀδÙ. °øÈ²¹ßÀÛÀÇ Áõ»óÀº ±Þ°ÝÇÑ ÀÚÀ²½Å°æÀÚ±ØÁõ»óÀ¸·Î È£Èí°ï¶õ, ½ÉÀå¹Úµ¿Ç×Áø, ÈäºÎÅëÁõ, ÈäºÎ¾Ð¹Ú°¨, Áú½Ä°¨, Çö±âÁõ, ºÒ¾ÈÁ¤ÇÑ ´À³¦ µîÀÌ´Ù. ´ë°³ °©ÀÚ±â ÀϾ ¼öºÐµ¿¾È Áö¼ÓÇß´Ù°¡ ¼Ò½ÇµÇ´Â °ÍÀÌ º¸ÅëÀÌ´Ù. µå¹°°Ô´Â ¼ö½Ã°£ Áö¼ÓµÇ±âµµ ÇÑ´Ù. °øÈ²¹ßÀÛÀº ÁÖ±âÀûÀ¸·Î ¹Ýº¹µÇ¸é¼ ¸¸¼ºÈÇÏ´Â °æÇâÀÌ ¸¹´Ù. ½Å°æ°ú¹ÎÀº °øÈ²¹ßÀÛÀÌ ¾ø´Â ½Ã±âÀÇ Áõ»óÀÌ´Ù. °¨´çŰ ¾î·Á¿î °øÈ²¹ßÀÛ¿¡ ´ëÇÑ ¿¹±âºÒ¾È(±× ÀÏÀÌ ÀϾÁö ¾ÊÀ»±î ÇÏ´Â ´À³¦ ¶§¹®¿¡ ¿À´Â ºÒ¾È)ÀÌ ÀÖ°í ±× ¶§¹®¿¡ Á¶½É½º·¯¿öÁö°í ÁÖÀ§¸¦ »ìÇǴ ŵµµµ ³ªÅ¸³ª¼ ½Å°æÀº ±Øµµ·Î ³¯Ä«·Î¿öÁø´Ù. °øÆ÷Àå¾Ö¿¡¼µµ ÀÌ·± °øÈ²¹ßÀÛÀÌ ¿Ã ¼ö ÀÖÀ¸³ª, ÀÌ °æ¿ì´Â Ưº°ÇÑ ´ë»óÀ̳ª »óȲÀÌ ÀÖ´Â °Í¿¡ ¹ÝÇØ °øÈ²Àå¾Ö´Â ÀÌ·± Ưº°ÇÑ »ç°Ç¾øÀÌ ÁÖ±âÀûÀ¸·Î ¹ß»ýÇÑ´Ù. Ä¡·á´Â Ç׺ҾÈÁ¦¿Í ¶§·Î´Â Ç׿ì¿ïÁ¦¸¦ »ç¿ëÇÑ´Ù. |
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| ¿µ¹® | antisocial personality disorder | ÇÑ±Û | ¹Ý»çȸÀûÀΰÝÀå¾Ö |
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| ¼³¸í | Áö¼ÓÀûÀ¸·Î ±×¸®°í ¸¸¼ºÀûÀ¸·Î ¹Ý»çȸÀûÀÎ ÇൿÀ» ÇÏ´Â Á¤½Å°úÀû º´. ´Ù¸¥ »ç¶÷¿¡°Ô Áø½Ç¼ºÀÌ ¾ø°í ´Ù¸¥ »ç¶÷ÀÇ ±Ç¸®³ª ÇÇÇØ¿¡´Â ÀüÇô ¹«°¨°¢ÇÏ°í ´ÜÁö ÀÚ½ÅÀÇ Ãæµ¿°ú ¿å±¸¿¡ ÀÇÇØ¼ ÇൿÀ» ÇÑ´Ù. ÀÚ½ÅÀÇ ½Ç¼ö¿¡ ´ëÇØ¼ ´Ù¸¥ »ç¶÷ÀÌ Ãæ°íÇÏ´Â °ÍÀ» ÂüÁö¸øÇϰí Ç×»ó ÀÚ½ÅÀÇ ¸¶À½´ë·Î¸¸ ÇÑ´Ù. |
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| ¿µ¹® | anxiety disorder | ÇÑ±Û | ºÒ¾ÈÀå¾Ö |
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| ¼³¸í | ½É¸®Àû ºÒ¾ÈÁ¤À̳ª ºÒ¾È µîÀ» ÁÖ Æ¯Â¡À¸·Î ÇÏ´Â Á¤½Å°úÀû º´ÅÂ. ´ëÇ¥ÀûÀÎ ¿¹·Î´Â °øÆ÷Áõ(phobia)¿Í °øÈ²Àå¾Ö(panic disorder), Àü¹ÝÀû ºÒ¾ÈÀå¾Ö(generalized anxiety disorder) µîÀÌ ÀÖ´Ù. °øÆ÷ÁõÀ̶õ ƯÁ¤ÇÑ Àå¼Ò³ª »óȲ¿¡ ´ëÇØ¼ º´ÀûÀÎ ºÒ¾ÈÀ» ´À³¢´Â °ÍÀ¸·Î ±¤Àå°øÆ÷Áõ(agoraphobia): Ź Æ®ÀÎ °ø°£À» ¹«¼¿öÇÔ. »çȸ°øÆ÷Ãþ(social phobia): ´Ù¸¥ »ç¶÷¾Õ¿¡ ¼´Â °ÍÀ» ¹«¼¿ö ÇÔ. °í¼Ò°øÆ÷Ãþ(acrophobia): ³ôÀº °÷¿¡ °¡´Â °ÍÀ» ¹«¼¿öÇÔ. ÁøÆó°øÆ÷Áõ(claustrophobia): ¹ÐÆóµÈ °ø°£À» ¹«¼¿öÇÔ. µ¿¹°°øÆ÷Áõ(zoophobia): µ¿¹°À» º´ÀûÀ¸·Î ¹«¼¿öÇÔ µîÀ» Æ÷ÇÔÇÑ´Ù. °øÈ²Àå¾Ö(panic disorde)¶õ ¿ÜºÎÀÇ À§ÇèÇÑ ÀÚ±ØÀÌ ¾ø´Âµ¥µµ ºÒ±¸ÇÏ°í °©Àڱ⠱ؽÉÇÑ °øÆ÷¸¦ ´À³¢´Â °ÍÀ» ¸»ÇÑ´Ù. ´ë°³ ½ÉÀåÀÌ ½ÉÇÏ°Ô ¶Ù°Å³ª ½ÄÀº ¶¡À» È긮°í, ½Ç½Å, È£Èí°ï¶õ µîÀÇ Áõ»óÀ» µ¿¹ÝÇÑ´Ù. Àü¹ÝÀû ºÒ¾ÈÀå¾Ö(generalized anxiety disorder)¶õ 1°³¿ùÀÌ»ó Áö¼ÓÀûÀÎ ºÒ¾ÈÀ» ´À³¢´Â °ÍÀ» ¸»ÇÑ´Ù. ´ë°³ »ç¼ÒÇÑ ÀÏ»óÀÇ ÀÏ¿¡ ´ëÇÑ ºÒ¾ÈÀ» ´À³¢¸ç, ºÒ¾ÈÀÇ ´ë»óÀÌ ¾ø´Â °æ¿ì¿¡´Â ¾ðÁ¦ ºÒ¾ÈÀ» ´À³¥Áö ¸ð¸¥´Ù´Â ºÒ¾È°¨(¿¹±âºÒ¾È)À» È£¼ÒÇÑ´Ù. ´ë°³ ¼è¾à, ¾îÁö·¯¿ò, ¼Õ¶³¸², ¶¡À» È긮´Â µîÀÇ ½ÅüÀû Áõ»óÀ» µ¿¹ÝÇÑ´Ù. |
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| CD | cadaver donor; canine distemper; canine dose; carbohydrate dehydratase; carbon dioxide; cardiac dise... |
|---|---|
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| DD | dangerous drug; data definition; day of delivery; degenerated disc; degenerative disease; delusional... |
| PAD | pain and distress; patient surface axis depth; percutaneous abscess drainage; percutaneous automated... |
| SPD | schizotypal personality disorder; sociopathic personality disorder; specific paroxysmal discharge; s... |
| BCE | Bone collagen equivalent |
|---|---|
| COL | Collagen |
| GAG | Collagen and glycosaminoglycan |
| CIA | Collagen induced arthritis |
| CII | Collagen type II |
| Mallory's collagen stain | <technique> One of a number of staining methods using phosphomolybdic or phosphotungstic acid with an acid stain, such as aniline blue, or with haematoxylin for connective tissue staining. (05 Mar 2000) |
|---|---|
| collagen | <protein> The protein substance of the white fibres (collagenous fibres) of skin, tendon, bone, cartilage and all other connective tissue, composed of molecules of tropocollagen, it is converted into gelatin by boiling. Collagenous pertaining to collagen, forming or producing collagen. Origin: Gr. Kolla = glue, gennan = to produce (18 Nov 1997) |
| collagen diseases | Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (12 Dec 1998) |
| collagen fibre | An individual fibre that varies in diameter from less than 1 um to about 12 um and is composed of fibrils; the fibre's, which are usually arranged in bundles, undergo some branching and are of indefinite length; chemically the fibre is a glycoprotein, collagen, which yields gelatin upon boiling; they make up the principal element of irregular connective tissue, tendons, aponeuroses, and most ligaments, and occur in the matrix of cartilage and osseous tissue. Synonym: white fibre. (05 Mar 2000) |
| collagen fibrils | The fibril's that comprise a collagen fibre, ranging from 20 to 200 nm and averaging about 100 nm in diameter (substantially larger in tendons), with cross-striations averaging 64 nm. Synonym: collagen fibrils. (05 Mar 2000) |
| collagen injection | Correction of superficial soft tissue deformities, acne scars, or age-related skin changes by injection (implantation) of collagen; bovine collagen preparations are commonly used. Prior intradermal testing is necessary to exclude hypersensitivity. (05 Mar 2000) |
| collagen telopeptidase | <enzyme> Neutral metalloproteinase from porcine gingiva; removes the extra-helical extension peptides proximal to the lysyl residue at position 17 Registry number: EC 3.4.24.- Synonym: collagen depolymerase (26 Jun 1999) |
| collagen-vascular diseases | A group of generalised disease's affecting connective tissue and frequently characterised by fibrinoid necrosis or vasculitis; in some collagen disease's, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue. See: connective-tissue diseases. (05 Mar 2000) |
| SLS collagen | <protein> Abnormal packing pattern of collagen molecules formed if ATP is added to acidic collagen solutions, in which lateral aggregates of molecules are produced. Each aggregate is 300 nm long and the molecules are all in register. If SLS aggregates are overlapped with a quarter stagger, the 67 nm banding pattern of normal fibrils is reconstituted. (19 Jan 1998) |
| type I collagen | The most abundant collagen, which forms large well-organised fibrils having high tensile strength. (05 Mar 2000) |
| type II collagen | Collagen unique to cartilage, nucleus pulposis, notochord, and vitreous body; it forms as thin highly glycosylated fibrils. (05 Mar 2000) |
| type III collagen | Collagen characteristic of reticular fibres. (05 Mar 2000) |
| type IV collagen | A less distinctly fibrillar form of collagen characteristic of basement membranes. (05 Mar 2000) |
| affective personality disorder | A disturbance of feelings or mood expressed as a milder form of depression and related emotional features that colour the whole psychic life and for which psychosocial stressors are believed to play the major role. (05 Mar 2000) |
| alcohol amnestic disorder | <psychiatry> A mental disorder with brain damage characterised by amnesia, compensatory confabulation, disturbance of attention, and peripheral neuritis. It is usually associated with alcoholism and dietary deficiencies. (12 Dec 1998) |
| collagen disorder |
any inborn error of metabolism involving abnormal structure or metabolism of collagen; the term includes Ehlers-Danlos syndrome, Marfan syndrome, cutis laxa, osteogenesis imperfecta, and epidermolysis bullosa. Collagen disorder is not to be confused with collagen disease (qv).
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