| cold haemagglutinin disease | A condition associated with the presence of haemagglutinating autoantibody active in vivo but in vitro particularly or solely active in the cold; when the concentration of IgM antibody is high there may be increased serum viscosity, but clinical manifestations (due to haemagglutination) usually appear following exposure to cold; haemolysis usually is mild but may be severe, resulting in autoimmune haemolytic anaemia, cold antibody type. (05 Mar 2000) |
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| haemagglutinin | <haematology> Substance that will bring about the agglutination of erythrocytes. (18 Nov 1997) |
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| haemagglutinin glycoproteins, influenza virus | Membrane glycoproteins from influenza viruses which are involved in haemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of ha glycoproteins and nine of na glycoproteins have been identified from influenza a virus; no subtypes have been identified for influenza b or influenza c viruses. (12 Dec 1998) |
| haemagglutinin-neuraminidase protein | <protein> A protein found in the capsid of the Sendai virus which is exceptionally good at binding to the cytoplasmic membranes of many animal cells. The protein is therefore used to make fusogenic vesicles for the purpose of delivering therapeutic drugs or other chemicals directly into cells. (09 Oct 1997) |
| haemagglutinin-protease | <enzyme> Soluble haemagglutinin/protease from vibrio cholerae; a zinc metalloendopeptidase Registry number: EC 3.4.24.- Synonym: ha-protease, vibrio cholerae haemagglutinin protease, vibrio cholerae non-o1 haemagglutinin-protease, nag-ha-p (26 Jun 1999) |
| paroxysmal cold haemoglobinuria | <haematology> A rare blood disorder caused by antibodies which destroy red blood cells upon exposure to the cold. The antibodies are formed against a specific blood group and are triggered by the cold. The cause is unknown but the disease has been associated with syphilis and some viral infections. Serum haemoglobin and urine haemoglobin are increased during the attacks. The disease is chronic and treatment is difficult. Some cases resolve spontaneously without treatment. Origin: Gr. Ouron = urine (27 Sep 1997) |
| rose cold | Allergic rhinitis occurring in the spring and early summer. (05 Mar 2000) |
| warm-cold haemolysin | Haemolysin which combines with red blood cells at temperatures below 20캜 and are eluted at warmer temperatures, e.g., 30 to 37캜. See: Donath-Landsteiner cold autoantibody, haemagglutinating cold autoantibody. (05 Mar 2000) |
| cold | <virology> A slang term that describes a viral upper respiratory infection which results from inflammation of the mucous membranes of the nasal cavity. (27 Sep 1997) |
| cold abscess | An abscess without heat or other usual signs of inflammation. Synonym: tuberculous abscess. (05 Mar 2000) |
| cold agglutination | The agglutination of red blood cells by their own serum (see autoagglutination), or by any other serum when the blood is cooled below body temperature, but most pronounced below 25캜; the phenomenon results from cold agglutinins; may be seen occasionally in the blood of apparently normal persons or as a pathologic finding in patients with primary atypical pneumonia, infectious mononucleosis, and other viral diseases, certain protozoan infections, or lymphoproliferative neoplasms. See: autoagglutination. (05 Mar 2000) |
| cold agglutination test | <investigation> A test for blood antibodies which are present in certain peculiar types of pneumonia (atypical pneumonia, Mycoplasma) (27 Sep 1997) |
| cold agglutinin | An antibody which reacts more efficiently at temperatures below 37캜. (05 Mar 2000) |
| cold agglutinins | <haematology> Antibodies that agglutinate particles with greater activity below 32쵣. They are IgM antibodies specifically reactive with blood groups I and i in humans and agglutinate red blood cells on cooling, causing Raynaud's phenomenon in vivo. (18 Nov 1997) |
| cold allergy | Physical symptoms produced by hypersensitivity to cold. (05 Mar 2000) |
| cold antibody | See: cold agglutinin. (05 Mar 2000) |