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col A crater-like area of the interproximal oral mucosa joining the lingual and buccal interdental papillae.
(05 Mar 2000)
col e1 <molecular biology> A plasmid which naturally occurs in some strains of the bacteria Escherichia coli.
It codes for an E. Coli-produced antibiotic called a colicin and immunity to its self-produced colicin (so that it does not unintentionally destroy itself). It is one of a number of such plasmids, each of which code for a different type of colicin. The plasmid is useful for making cloning vectors for making recombinant DNA molecules.
(09 Oct 1997)
Col V A plasmid of E. Coli that codes for colicin V, that confers resistance to complement mediated killing, for a siderophore to scavenge iron and for f like pili that permit conjugation.
(18 Nov 1997)
cola Synonym: kola.
Origin: L., Strain (imperative form).
(05 Mar 2000)
colcemid <drug> Methylated derivative of colchicine.
(18 Nov 1997)
colchicine <drug> Alkaloid (400 D) isolated from the Autumn crocus (Colchicum autumnale) that blocks microtubule assembly by binding to the tubulin heterodimer (but not to tubulin).
As a result of interfering with microtubule reassembly will block mitosis at metaphase.
(18 Nov 1997)
colchicum A genus of poisonous, liliaceous plants. The roots (corms) of colchicum autumnale, the fall crocus or meadow saffron, yield colchicine, which is used as a biochemical tool and to treat gout. Other members of this genus yield saffron dye, flavoring agents, and aromatics.
(12 Dec 1998)
Colchicum corm Dried corm of Colchicum autumnale, the botanical source for colchicine, an alkaloidal drug used for the treatment of gout.
(05 Mar 2000)
cold <virology> A slang term that describes a viral upper respiratory infection which results from inflammation of the mucous membranes of the nasal cavity.
(27 Sep 1997)
cold abscess An abscess without heat or other usual signs of inflammation.
Synonym: tuberculous abscess.
(05 Mar 2000)
cold agglutination The agglutination of red blood cells by their own serum (see autoagglutination), or by any other serum when the blood is cooled below body temperature, but most pronounced below 25°C; the phenomenon results from cold agglutinins; may be seen occasionally in the blood of apparently normal persons or as a pathologic finding in patients with primary atypical pneumonia, infectious mononucleosis, and other viral diseases, certain protozoan infections, or lymphoproliferative neoplasms.
See: autoagglutination.
(05 Mar 2000)
cold agglutination test <investigation> A test for blood antibodies which are present in certain peculiar types of pneumonia (atypical pneumonia, Mycoplasma)
(27 Sep 1997)
cold agglutinin An antibody which reacts more efficiently at temperatures below 37°C.
(05 Mar 2000)
cold agglutinins <haematology> Antibodies that agglutinate particles with greater activity below 32­C. They are IgM antibodies specifically reactive with blood groups I and i in humans and agglutinate red blood cells on cooling, causing Raynaud's phenomenon in vivo.
(18 Nov 1997)
cold allergy Physical symptoms produced by hypersensitivity to cold.
(05 Mar 2000)
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