| cocaine | <drug> Drug of abuse and psychostimulant that acts to increase extraneuronal dopamine in midbrain by binding to the dopamine uptake transporter and hence inhibiting dopamine reuptake at the plasma membrane. (18 Nov 1997) |
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| cocaine abuse | <psychiatry> Cocaine is an alkaloid, derived from the coca plant. It is used medicinally as a topical anaesthetic (commonly in the nose). It may cause agitation, disorientation and convulsions. Cocaine is a commonly abused street drug and can lead to addictive behaviour. (27 Sep 1997) |
| cocaine esterase | <enzyme> Aspect of carboxylesterase Registry number: EC 3.1.1.- Synonym: (-)-cocaine-3-acylhydrolase, cocaine carboxylesterase (26 Jun 1999) |
| cocaine-related disorder | <psychiatry> Disorders related or resulting from use of cocaine. (12 Dec 1998) |
| crack cocaine | The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. There are concomitant psychological and social alterations as well. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking. (12 Dec 1998) |