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coca Any of several south american shrubs of the erythroxylon genus (and family) that yield cocaine; the leaves are chewed with alum for CNS stimulation.
(12 Dec 1998)
cocaine <drug> Drug of abuse and psychostimulant that acts to increase extraneuronal dopamine in midbrain by binding to the dopamine uptake transporter and hence inhibiting dopamine reuptake at the plasma membrane.
(18 Nov 1997)
cocaine abuse <psychiatry> Cocaine is an alkaloid, derived from the coca plant. It is used medicinally as a topical anaesthetic (commonly in the nose).
It may cause agitation, disorientation and convulsions. Cocaine is a commonly abused street drug and can lead to addictive behaviour.
(27 Sep 1997)
cocaine esterase <enzyme> Aspect of carboxylesterase
Registry number: EC 3.1.1.-
Synonym: (-)-cocaine-3-acylhydrolase, cocaine carboxylesterase
(26 Jun 1999)
cocaine-related disorder <psychiatry> Disorders related or resulting from use of cocaine.
(12 Dec 1998)
cocainization <anaesthetics> Production of topical anaesthesia of mucous membranes by the application of cocaine.
(05 Mar 2000)
cocarboxylase The diphosphoric ester of thiamin, a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Synonym: aneurine pyrophosphate, cocarboxylase, diphosphothiamin.
(05 Mar 2000)
cocarcinogen <oncology> A substance that works symbiotically with a carcinogen in the production of cancer. A helper in the role of a carcinogen.
A substances that, though not carcinogenic in its own right, potentiates the activity of a carcinogen. They differ from tumour promotors in requiring to be present concurrently with the carcinogen.
(21 Jun 2000)
cocarcinogenesis <oncology> The combination of two or more different factors in the production of cancer.
(12 Dec 1998)
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