| cluster analysis | A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both. (12 Dec 1998) |
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| breakpoint cluster region | A region on chromosome 22 that is involved in the Philadelphia translocation. Acronym: BCR (15 Nov 1997) |
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| gene cluster | A set of closely related genes that code for the same or similar proteins and which are usuallygrouped together on the same chromosome. (09 Oct 1997) |
| cluster headache | <symptom> A term used to describe a headache that is typified by constant, unilateral pain around the eye, with onset usually within 2-3 hours of falling asleep. Can be accompanied by a blocked nasal passage, runny nose, and-or tearing. One may also notice facial flushing, ptosis (dropping eyelid), facial swelling and constriction of the pupils. (27 Sep 1997) |
| cluster of differentiation | Cell membrane molecules that are used to classify leukocytes into subsets. CD molecules are classified by monoclonal antibodies. (05 Mar 2000) |
| cluster of differentiation 2 | A glycoprotein that is expressed on all peripheral T-cells, large granular lymphocytes and most, but not all, thymocytes. CD2 is involved in signal transduction and cell adhesion. (05 Mar 2000) |
| cluster of differentiation 3 | A complex of 5 polypeptides associated with the T-cell receptor and is involved in signal transduction. (05 Mar 2000) |
| cluster of differentiation 4 | A glycoprotein found on various subsets of T-cells, i.e., usually no helper and some T cytotoxic cells. (05 Mar 2000) |
| cluster of differentiation 8 | Membrane glycoprotein found on subsets of T lymphocytes. CD8 is expressed on T cytotoxic cells and T suppressor cells. Acronym: CD (05 Mar 2000) |
| egg cluster | One of the clumps of cells resulting from the breaking up of the gonadal cords in the ovarian cortex; these clumps later develop into primary ovarian follicles. (05 Mar 2000) |
| accumulation analysis | A technique in which an intermediate of a metabolic pathway accumulates due to selective inhibition of a particular step in that pathway or in a mutant that is deficient in a certain step. The intermediate is then isolated, analyzed, and identified. (05 Mar 2000) |
| activation analysis | <radiobiology> Method for identifying and measuring chemical elements in a sample of material. Sample is first made radioactive by bombardment with neutrons, charged particles, or gamma rays. Newly formed radioactive atoms in the sample then give off characteristic radiations (such as gamma rays) that tell what kinds of atoms are present, and how many. (09 Oct 1997) |
| actuarial analysis | The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs. (12 Dec 1998) |
| amino acid analysis | Determination and identification of amino acid content of a macromolecule, identification of a specific amino acid in macromolecules, often a mutated protein, identification and quantitation of amino acid content in blood plasma or urine; a key diagnostic aid. (05 Mar 2000) |
| analysis | <technique> The separation into component parts or elements, the act of determining the component parts of a substance. Origin: Gr. Lysis = dissolution (18 Nov 1997) |
| analysis of variance | A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. (12 Dec 1998) |