| hemophilia | <disease, haematology> A haemorrhagic diathesis occurring in two main forms: 1. Haemophilia A (classic haemophilia, factor VIII deficiency), an X linked disorder due to deficiency of coagulation factor VIII. 2. Haemophilia B (factor IX deficiency, Christmas disease), also X linked, due to deficiency of coagulation factor IX. Both forms are determined by a mutant gene near the telomere of the long arm of the X chromosome (Xq), but a different loci and are characterised by subcutaneous and intramuscular haemorrhages, bleeding from the mouth, gums, lips and tongue, haematuria and haemarthroses. (18 Nov 1997) |
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| migraine, classic | Migraine with aura. Accounts for no more than most 20% of migraines. See migraine. (12 Dec 1998) |
| classic | Of first class of rank, standard. (18 Nov 1997) |
| classic cervical rib syndrome | <syndrome> Very chronic axon loss brachial plexopathy, caused by compromise of the lower trunk fibres by a congenital band extending from a rudimentary cervical rib to the first thoracic rib; rare disorder, found mostly in young to middle-aged women, that presents with unilateral hand wasting and weakness, particularly involving the lateral thenar eminence; sometimes accompanied by intermittent discomfort along the medial forearm and hand. Synonym: cervical rib and band syndrome, classic cervical rib syndrome. (05 Mar 2000) |
| classic migraine | A form of hemicrania migraine preceded by a scintillating scotoma (teichopsia). (05 Mar 2000) |
| typhus, classic | See Typhus, epidemic. (12 Dec 1998) |