| class I antigen |
One of the major histocompatibility molecules present on almost all cells except human red blood cells. These antigens are important in the rejection of grafts and transplanted organs.
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| class II antigen |
One of the major histocompatibility molecules present on immunocompetent cells.
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| class I a.’s |
major histocompatibility antigens found on virtually every cell, human erythrocytes being the only notable exception; they are found on molecules consisting of two noncovalently bound chains. One, a 44,000-dalton polymorphic glycoprotein partially embedded in the cell membrane, is determined by an MHC gene (HLA-A, -B, or -C in humans); the other, β2-microglobulin, a 12,000-dalton nonpolymorphic protein, is determined by a non-MHC gene. Class I antigens are the classic histocompatibility antigens recognized during graft rejection and are also the antigens involved in MHC restriction (q.v.).
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| class II a.’s |
major histocompatibility antigens found only on immunocompetent cells, primarily B lymphocytes and macrophages; they are found on molecules consisting of two noncovalently bound chains, the 34,000-dalton α chain and 29,000-dalton β chain, both glycoproteins partially embedded in the cell membrane and both determined by MHC genes. The human HLA-D, -DR, -DQ, -DT, -MB, -MT, and -Te loci are all associated with antigenic determinants on class II antigen molecules.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| class III a.’s |
a term used to refer to nonhistocompatibility antigens mapping in the major histocompatibility complex, e.g., the complement components C2, C4, factor B.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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