| 영문 | toxicity | 한글 | 독성 |
|---|---|---|---|
| 설명 | 생체에 있어 바람직하지 않은 약물 작용을 말한다. 약물을 과량으로 사용하면 중독을 일으키며, 심한 경우에는 죽음에 이르는데 이는 약물의 급성 독성이다. 만성 독성은 소량을 장기간 반복 섭취하였을 때의 독성이다. 간, 콩팥 등 여러 장기와 조직에 대한 독성 외에, 기형유발성, 발암성 등도 약물독성이다. 약물독성의 강약은 급성 독성검사(LD50), 만성 독성검사, 기형유발검사, 발암검사, 번식검사 기타 여러 동물검사에 의해 판정된다. |
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| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
|---|---|
| ACD | absolute cardiac dullness; absolute claudication distance; acid-citrate-dextrose [solution]; actinom... |
| SSC | single-strand conformational [analysis]; sister strand crossover; somatosensory cortex; standard sal... |
| EUROTOX | European Committee on Chronic Toxicity Hazards |
| I&T | intolerance and toxicity |
| CTC | Common Toxicity Criteria |
|---|---|
| DLT | Dose limiting toxicity |
| RRT | Regimen related toxicity |
| TCLP | Toxicity Characteristic Leaching Procedure |
| TIE | Toxicity Identification Evaluation |
| acute toxicity | <pharmacology> Illness resulting from a single dose or exposure to a toxic substance. Compare: chronic toxicity. (06 May 1997) |
|---|---|
| chronic toxicity | <pharmacology> Illness caused by repeated or long-term exposure to low doses of a toxic substance. Compare: acute toxicity. (09 Oct 1997) |
| digitalis toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| digoxin toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| drug toxicity | The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. (27 Sep 1997) |
| oxygen toxicity | A body disturbance resulting from breathing high partial pressures of oxygen; characterised by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation. Synonym: oxygen poisoning. (05 Mar 2000) |
| toxicity | The quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. (18 Nov 1997) |
| toxicity test | <investigation> Controlled laboratory test to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations. An acute toxicity test establishes the concentration required to kill a predetermined proportion of test organisms within a relatively short period of time, typically 4 days or less. A chronic toxicity test reveals the effects of a sublethal concentration applied throughout all or part of the life cycle. (12 Jan 1998) |
| toxicity tests | Tests that determine the toxicity of a substance. These include tests of clinical drugs, foods, environmental pollutants, etc. (12 Dec 1998) |
| ep toxicity | A test defined by the federal Environmental Protection Agency to check a substance for the presence of arsenic, barium, cadmium, chromium, lead, mercury, selenium, or silver. 40 CFR 261.24 defines the concentrations constituting hazardous waste and the test procedure. (05 Dec 1998) |
| acid-citrate-dextrose | A citrate anticoagulant used for the collection and preservation of whole blood. It has largely been replaced by newer coagulants (CPD, Adsol) that allow for longer shelf life for blood and blood products. Acronym: ACD (05 Mar 2000) |
| ATP citrate lyase | ATP citrate (pro-3S)-lyase |
| ATP citrate (pro-3S)-lyase | <enzyme> An enzyme that, in the presence of ATP and CoA, catalyses the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and orthophosphate. This reaction represents an important step in fatty acid biosynthesis. Chemical name: ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating) Registry number: EC 4.1.3.8 Synonym: citrate cleavage enzyme. (12 Dec 1998) |
| bismuth ammonium citrate | Ammoniocitrate of bismuth; an intestinal astringent. (05 Mar 2000) |
| bismuth citrate | Used in the making of bismuth and ammonium citrate. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|