| chronic nonleukaemic myelosis | A condition in which there is abnormal proliferation of leukopoietic tissue that results in immature white blood cells in the circulating blood, but the total count is within the normal range. (05 Mar 2000) |
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| aleukaemic myelosis | Myelosis with absence of abnormal cellular elements in peripheral blood. (05 Mar 2000) |
| myelosis | 1. A condition characterised by abnormal proliferation of tissue or cellular elements of bone marrow, e.g., multiple myeloma, myelocytic leukaemia, myelofibrosis. 2. A condition in which there is abnormal proliferation of medullary tissue in the spinal cord, as in a glioma. (05 Mar 2000) |
| subleukaemic myelosis | A form of leukaemia in which abnormal cells are present in the peripheral blood, but the total leukocyte count is not elevated. Synonym: hypoleukaemia, leukopenic myelosis, subleukaemic myelosis, subleukaemia. (05 Mar 2000) |
| erythraemic myelosis | A neoplastic process involving the erythropoietic tissue, characterised by anaemia, irregular fever, splenomegaly, hepatomegaly, haemorrhagic disorders, and numerous erythroblasts in all stages of maturation (with disproportionately large numbers of less mature forms) in the circulating blood; postmortem studies reveal primitive erythroblasts and reticuloendothelial cells, not only in haemopoietic organs, but also in the kidneys, adrenal glands, and other sites. Acute and chronic forms are recognised, but in the latter there is less prominence of the immature cells; the former is also called Di Guglielmo's disease and acute erythraemia. (05 Mar 2000) |
| funicular myelosis | Degeneration of spinal cord white matter. (05 Mar 2000) |
| leukaemic myelosis | <haematology, tumour> A form of leukaemia characterised by an uncontrolled proliferation of myelopoietic cells in the bone marrow and in extramedullary sites, and the presence of large numbers of immature and mature granulocytic forms in various tissues (and organs) and in the circulating blood. The total count may range from 1000 (aleukaemic variety) to several hundred thousand per cu mm. The predominant cell is usually of the neutrophilic series, but, in a few instances, eosinophilic or basophilic granulocytes, or even megakaryocytes, may represent the chief form; early in granulocytic leukaemia, the circulating blood may contain excessive numbers of all of the granulocytic forms. Synonym: leukaemic myelosis, myelocytic leukaemia, myelogenic leukaemia, myelogenous leukaemia, myeloid leukaemia. (05 Mar 2000) |
| anaemia of chronic disease | <disease> A form of anaemia which develops as the result of a long-term infection or illness. Chronic diseases can interfere with red blood cell production in addition to shortening red blood cell life span in the body. Symptoms are largely due to the underlying disease. Haemoglobin and haematocrit are generally low. Iron studies may be low to normal. Red blood cell indices may usually normal. (27 Sep 1997) |
| benign familial chronic pemphigus | Recurrent eruption of vesicles and bullae that become scaling and crusted lesions with vesicular borders, predominantly of the neck, groin, and axillary regions; autosomal dominant inheritance, presenting in late adolescence or early adult life. Synonym: Hailey-Hailey disease. (05 Mar 2000) |
| candidiasis, chronic mucocutaneous | A clinical syndrome characterised by development, usually in infancy or childhood, of a chronic, often widespread candidiasis of skin, nails, and mucous membranes. It may be secondary to one of the immunodeficiency syndromes, inherited as an autosomal recessive trait, or associated with defects in cell-mediated immunity, endocrine disorders, dental stomatitis, or malignancy. (12 Dec 1998) |
| granulomatous disease, chronic | A recessive x-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. (12 Dec 1998) |
| persistent chronic hepatitis | A benign chronic hepatitis that may follow acute viral hepatitis A or B, or complicate bowel diseases; after six months, liver biopsy changes are mild, unlike active chronic hepatitis; rarely, if ever, progresses to cirrhosis, portal hypertension, or liver failure. (05 Mar 2000) |
| chronic | Persisting over a long period of time. Origin: L. Chronicus, Gr. Chronos = time (18 Nov 1997) |
| chronic abscess | A long-standing collection of pus surrounded by fibrous tissue. (05 Mar 2000) |
| chronic absorptive arthritis | Arthritis accompanied by pronounced resorption of bone with shortening and deformity, especially of the hands; when the deformity is extreme, the condition has also been termed arthritis mutilans. (05 Mar 2000) |