| 영문 | mutation | 한글 | 돌연변이 |
|---|---|---|---|
| 설명 | 세포의 dna 자체의 변이에 의해 일어나는 세포변이를 말한다. 이러한 경우 돌연변이로 일어난 세포는 그 이후 딸세포(daughter cell)에서도 그 변이가 여전히 유지되므로 종(species)의 변화나, 혹은 세포의 악성변환(malignant transformation)에 관여한다. |
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| 영문 | sex chromosome | 한글 | 성염색체 |
|---|---|---|---|
| 설명 | 암수의 성을 결정하는 데 중요한 구실을 하는 염색체. 이것에 대하여 보통의 염색체를 보통염색체라고 한다. 암수의 구별이 있는 생물에서는 암수에 따라 다른 형과 수를 나타내는 염색체이며, 보통염색체에 비해 염색성이나 행동에서 차이가 있다. 특히 동물의 성염색체는 그런 경향이 강하다. 휴지기 및 핵분열 전기에 뚜렷한 이상응축을 나타내며 감수분열 때는 다른 염색체보다 먼저 앞서거나 끌려가는 행동을 보여준다. |
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| 영문 | chromosome | 한글 | 염색체 |
|---|---|---|---|
| 설명 | 유전정보를 담고 있는 DNA가 모여서 이루는 구조물로 핵속에 위치한다. 세포가 분열할 때 이것을 더욱 뚜렷이 관찰할 수가 있다. 이것은 사람처럼 고등생물체에서 너무나 많은 정보를 담고 있어, 엄청난 길이(사람에 있어서 전 DNA를 길이로 따지면 약 2m가 된다)가 된 DNA를 작은 핵이란 공간속에 보관하기 위해서 만들어진 구조이다. 이 염색체의 수는 생물의 종에 따라 다르며 사람의 경우는 46개이다. |
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| 영문 | chromosome abnormality | 한글 | 염색체이상 |
|---|---|---|---|
| 설명 | 염색체의 수나 구조의 이상. 이상이 생긴 세포나 개체는 유전적인 이상을 일으켜 사람의 경우, 다운 증후군-터너 증후군 따위의 여러 가지 형태로 나타난다. |
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| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| Xp | paternal chromosome X; short arm of chromosome X |
| Xi | inactive X Chromosome |
| ARMS | Amplification Refractory Mutation System |
|---|---|
| MFD | Mutation frequency decline |
| RIP | Repeat Induced Point mutation |
| RSM | Restriction Site Mutation |
| SMART | Somatic Mutation And Recombination Test |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
|---|---|
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |
| germ-line mutation | Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (12 Dec 1998) |
| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| chromosomal mutation | Can refer to any of a number of DNA mutations which results in a change in the protein encoded by the mutated gene, such as point mutations, insertion or deletion mutations (frameshift mutations), or nonsense mutations. More often this refers to mutations involving chromosomes, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair, a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells. (09 Oct 1997) |
| missense mutation | <molecular biology> A mutation that alters a codon for a particular amino acid to one specifying a different amino acid. (18 Nov 1997) |
| conditional mutation | <molecular biology> A mutation that is only expressed under certain environmental conditions for example temperature sensitive mutants. (05 Jan 1998) |
| point mutation | <molecular biology> Mutation that causes the replacement of a single base pair with another pair. (18 Nov 1997) |
| polar mutation | <molecular biology> A mutation in a single gene which affects the rate of expression of other genes that are near it on a chromosome. (09 Oct 1997) |
| mutation | 1. A change in form, quality or some other characteristic. 2. <genetics> A permanent transmissible change in the genetic material, usually in a single gene. Also, an individual exhibiting such a change. Also called (in classical genetics) a sport. Origin: L. Mutatio from mutare = to change (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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