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an irregularity in the number or structure of chromosomes that may alter the course of development of the embryo, usually in the form of a gain (duplication), loss (deletion), exchange (translocation), or alteration in sequence (inversion) of genetic material. See Plate 1 and see genetic disease, under disease. Click here to view imagePLATE 1—CHROMOSOME ABERRATIONS■Genes are indicated by letters; breaks are indicated by small arrows.
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