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cholinester An ester of choline; e.g., acetylcholine.
(05 Mar 2000)
cholinesterase <enzyme> An enzyme that breaks down acetylcholine tostop its action.
(22 May 1997)
cholinesterase inhibitor <pharmacology> These are substances which which act to inhibit acetylcholinesterase, the enzyme which breaks down acetylcholine and thus enhance and subsequently prevent transmission of nerve impulses from one nerve cell to another or to a muscle.
Examples include pyridostigmine, ambenonium and neostigmine.
(15 Jan 1998)
cholinesterase reactivator A drug that reacts directly with the alkylphosphorylated enzyme to free the active unit; the drugs used therapeutically to reactivate phosphorylated forms of acetylcholinesterase are oximes, e.g., diacetylmonoxime, monoisonitrosoacetone, 2-pralidoxime.
(05 Mar 2000)
cholinesterase reactivators Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.
(12 Dec 1998)
cholinesterases <enzyme> Chemical name: Acylcholine acylhydrolase
Registry number: EC 3.1.1.8
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Cholinesterase Inhibitors - »õâ Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
    Synonyms : Anti-Cholinesterases, Anticholinesterase Drugs, Anticholinesterases, Cholinesterase Inhibitors, Irreversible, Cholinesterase Inhibitors, Reversible, Agents, Anticholinesterase, Anti Cholinesterases, Drugs, Anticholinesterase, Inhibitors, Acetylcholinesterase
  • Cholinesterase Reactivators - »õâ Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.
    Synonyms : Antagonists, Organophosphate Insecticide, Antagonists, Organothiophosphate Insecticide, Insecticide Antagonists, Organophosphate, Insecticide Antagonists, Organothiophosphate, Reactivators, Cholinesterase
  • Cholinesterases - »õâ
    Synonyms : Acylcholineacylhydrolase, Cholase, Cholinesterase
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cholinesterase an enzyme that hydrolyses acetylcholine (into choline and acetic acid)
Ãâó: wordnet.princeton.edu/perl/webwn
cholinesterase An enzyme that metabolizes the neurotransmitter acetylcholine. Cholinesterase inhibitors lead to increased levels of acetylcholine in the brain.
Ãâó: www.nature.com/nrd/journal/v2/n4/glossary/nrd1061_...
cholinesterase An enzyme found in animals that regulates nerve impulses. Cholinesterase inhibition is associated with a variety of acute symptoms such as nausea, vomiting, blurred vision, stomach cramps, and rapid heart rate.
Ãâó: www.nsc.org/ehc/glossary.htm
cholinesterase An enzyme that breaks down acetylcholine, into active parts that can be recycled.
Ãâó: www.alz.org/Resources/Glossary.asp
cholinesterase i. a compound that prevents the hydrolysis of acetylcholine by acetylcholinesterase, permitting high levels of acetylcholine to accumulate at reactive sites. Some are used as drugs, some are insecticides, and certain potent ones are nerve gases that can be deadly to humans or other animals. Called also anticholinesterase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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cholinester an enzyme that hydrolyses acetylcholine (into choline and acetic acid)
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