| cholinester | An ester of choline; e.g., acetylcholine. (05 Mar 2000) |
|---|---|
| cholinesterase | <enzyme> An enzyme that breaks down acetylcholine tostop its action. (22 May 1997) |
| cholinesterase inhibitor | <pharmacology> These are substances which which act to inhibit acetylcholinesterase, the enzyme which breaks down acetylcholine and thus enhance and subsequently prevent transmission of nerve impulses from one nerve cell to another or to a muscle. Examples include pyridostigmine, ambenonium and neostigmine. (15 Jan 1998) |
| cholinesterase reactivator | A drug that reacts directly with the alkylphosphorylated enzyme to free the active unit; the drugs used therapeutically to reactivate phosphorylated forms of acetylcholinesterase are oximes, e.g., diacetylmonoxime, monoisonitrosoacetone, 2-pralidoxime. (05 Mar 2000) |
| cholinesterase reactivators | Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates. (12 Dec 1998) |
| cholinesterases | <enzyme> Chemical name: Acylcholine acylhydrolase Registry number: EC 3.1.1.8 (12 Dec 1998) |