| chemotactic factors | Chemical substances that attract or repel cells or organisms. The concept denotes especially those factors released as a result of tissue injury, invasion, or immunologic activity, that attract leukocytes, macrophages, or other cells to the site of infection or insult. (12 Dec 1998) |
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| chemotactic factors, eosinophil | Cytotaxins liberated from normal or invading cells that specifically attract eosinophils; they may be complement fragments, lymphokines, neutrophil products, histamine or other; the best known is the tetrapeptide ecf-a, released mainly by mast cells. (12 Dec 1998) |
| chemotactic factors, macrophage | Cytotaxins liberated from normal or invading cells that specifically attract macrophages. They may be lymphokines, products of antigen, antibody and complement interactions or other. (12 Dec 1998) |
| monocyte chemotactic and activating factor | Cytokine of the C C subfamily, co induced with IL-8 on stimulation of endothelial cells, fibroblasts or monocytes that activates and is chemotactic for, monocytes. A chemokine. (18 Nov 1997) |
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| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| complement chemotactic factor | The activated complex of the fifth, sixth, and seventh components of complement (C567) which induces chemotaxis in the case of polymorphonuclear leukocytes. (05 Mar 2000) |
| eosinophil chemotactic factor of anaphylaxis | A peptide (MW 500 to 600) that is chemotactic for eosinophilic leukocytes and is released from disrupted mast cells. (05 Mar 2000) |
| chemotactic | A response of motile cells or organisms in which the direction of movement is affected by the gradient of a diffusible substance. Differs from chemokinesis in that the gradient alters probability of motion in one direction only, rather than rate or frequency of random motion. (18 Nov 1997) |
| chemotactic protein methylesterase | <enzyme> Demethylates methyl-accepting chemotaxis proteins Registry number: EC 3.1.1.- Synonym: chemotactic methylesterase, carboxymethylesterase of chemotaxis, cheb methylesterase (26 Jun 1999) |
| eosinophil chemotactic peptide | <protein> Tetrapeptides (of which two are identified: VGSE and AGSE) released by mast cells and that are said to both attract and activate eosinophils. (18 Nov 1997) |
| accelerator factor | <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease. Chemical name: Blood-coagulation factor V (12 Dec 1998) |
| acetate replacement factor | <biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms. (18 Nov 1997) |
| adrenal weight factor | A postulated substance of adenohypophysial origin responsible for maintenance of the weight of the adrenal cortex. (05 Mar 2000) |
| adrenocorticotropic releasing factor | Hormone produced by hypothalamus that causes pituitary to secrete adrenocorticotropic hormone. (05 Mar 2000) |
| a-factor | <molecular biology> A protein which is found in the bacterial genus Streptomyces that helps start the production of streptomycin and the process of morphological differentiation. It is used in biotechnology to induce these functions in mutant strains of Streptomyces that cannot produce it themselves. (09 Feb 1998) |
| angiogenesis factor | Substance causing proliferation of new blood vessels. It is found in tissues with high metabolic requirements, such as the retina, and in certain cancers. The factor is also released by hypoxic macrophages at the edges or outer surfaces of wounds and initiates revascularization in wound healing. (12 Dec 1998) |
| animal protein factor | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| antialopecia factor | A member of the vitamin B complex necessary for growth of yeast and of mice, absence from the diet causes hair loss and dermatitis in mice. (27 Sep 1997) |