| ceramide | <chemical> An N acyl sphingosine, the lipid moiety of glycosphingolipids. (18 Nov 1997) |
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| ceramide 1-phosphorylcholine | <biochemistry> A sphingolipid in which the head group is phosphoryl choline. A close analogue of phosphatidylcholine. In many cells the concentration of sphingomyelin and phosphatidylcholine in the plasma membrane seems to bear a reciprocal relationship. (18 Nov 1997) |
| ceramide cholinephosphotransferase | <enzyme> Do not confuse with phosphatidylcholine-ceramide phosphotransferase which is also called sphingomyelin synthase Registry number: EC 2.7.8.3 Synonym: sphingomyelin synthetase, phosphorylcholine-ceramide transferase, cdpcholine-n-acylsphingosine cholinephosphotransferase (26 Jun 1999) |
| ceramide dihexoside | The accumulated glycolipid noted in glycolipid lipidosis. (05 Mar 2000) |
| ceramide glycanase | <enzyme> Glycosphingolipid splitting enzyme from leech; cleaves linkage between oligosaccharide and ceramide Registry number: EC 3.2.1.- Synonym: cer glycanase (26 Jun 1999) |
| ceramide kinase | <enzyme> Catalyses the conversion of ceramide to ceramide 1-phosphate; calcium dependent Registry number: EC 2.7.1.138 (26 Jun 1999) |
| ceramide lactosidase | A hydrolytic enzyme (a beta-galactosidase) that acts on ceramide lactoside, producing glucosylceramide and galactose. A deficiency of this enzyme can result in ceramide lactoside liposis. Compare: cytolipin. (05 Mar 2000) |
| ceramide lactoside | A lactosylceramide that accumulates in individuals with ceremide lactoside liposis. Compare: cytolipin. (05 Mar 2000) |
| ceramide lactoside lipidosis | An inherited disorder associated with an accumulation of ceramide lactoside due to a deficiency of ceramide lactosidase; results in progressive brain damage with liver and spleen enlargement. (05 Mar 2000) |
| ceramide saccharide | <biochemistry> Ceramide derivatives containing more than one sugar residue. If sialic acid is present these are called gangliosides. (18 Nov 1997) |
| ceramide trihexosidase | <enzyme> An enzyme that catalyses the hydrolysis of a ceramidetrihexoside to a ceramidedihexoside plus galactose. Chemical name: D-Galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase Registry number: EC 3.2.1.47 (12 Dec 1998) |
| ceramide-activated protein kinase | <enzyme> Mw 97 kD; stimulation of kinase takes place during sphingomyelin pathway; has membrane-bound activity capable of phosphorylating a peptide derived from the sequence surrounding thr(699) of the epidermal growth factor receptor; has role in signal transduction for tumour necrosis factor Registry number: EC 2.7.10.- Synonym: cap kinase (26 Jun 1999) |
| ceramide-activated protein phosphatase | <enzyme> Belongs to the heterotrimeric subfamily of the pp2a group of serine-threonine protein phosphatases; involved in ceramide-mediated signal transduction; inhibited by okadaic acid Registry number: EC 3.1.3.- Synonym: ceramide-stimulated phosphatase, capp (enzyme) (26 Jun 1999) |
| phosphatidylcholine-ceramide phosphocholine transferase | <enzyme> Cdpcholine is not a donor; imvolved in sphingomyelin synthesis Registry number: EC 2.7.8.- Synonym: pc-cer-pch transferase, sphingomyelin synthase (26 Jun 1999) |
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| phosphatidylethanolamine-ceramide phosphoethanolamine transferase | <enzyme> Cdpethanolamine is not a donor; involved in sphingomyelin synthesis Registry number: EC 2.7.8.- Synonym: pe-cer-pet transferase (26 Jun 1999) |
| phosphatidylinositol-ceramide phosphoinositol transferase | <enzyme> Involved in biosynthesis of inositol-containing sphingolipids; isolated from saccharomyces cerevisiae Registry number: EC 2.4.1.- Synonym: ipc synthase (26 Jun 1999) |
| sphingolipid ceramide N-deacylase | <enzyme> Hydrolyzes the n-acyl linkage between fatty acids and sphingosine bases in ceramides in various sphingolipids, as well as sphingomyelin to produce their lyso forms; mw 52 kD Registry number: EC 3.5.1.- Synonym: scdase (26 Jun 1999) |