| ceramidase |
[EC 3.5.1.23] an enzyme of the hydrolase class that catalyzes the cleavage of a ceramide (N-acylsphingosine) to form sphingosine and a fatty acid anion, a step in the degradation of sphingolipids. Acid, neutral, and alkaline isozymes occur; deficiency of the acid (lysosomal) enzyme, an autosomal recessive trait, results in accumulation of ceramides and gangliosides in Farber's disease. Called also acylsphingosine deacylase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| ceramidase deficiency |
Farber's disease.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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