| B-cell differentiation/growth factors | Various substances, usually obtained from the supernatant of T-cell cultures, such as interleukin 4, 5, and 6. These substances are necessary for B-cell growth, maturation, and differentiation into plasma cells or B memory cells. (05 Mar 2000) |
|---|---|
| cell growth | <cell biology> Usually used to mean increase in the size of a population of cells though strictly should be reserved for an increase in cytoplasmic volume of an individual cell. (26 Mar 1998) |
| haematopoietic cell growth factors | These growth factors comprise a family of haematopoietic regulators with biological specificities defined by their ability to support proliferation and differentiation of blood cells of different lineages. Erythropoietin and the colony-stimulating factors belong to this family. Some of these factors have been studied and used in the treatment of chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow failure syndromes. (12 Dec 1998) |
| stem cell growth factors | <growth factor> Compounds, usually proteins, that make stem cells grow faster. (26 Mar 1998) |
| T-cell growth factor | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-1 | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-2 | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
| airspace-filling pattern | Cloudy to dense opacities, obscuring vascular markings, on chest radiographs. Synonym: airspace-filling pattern. (05 Mar 2000) |
| airway pattern | Chest radiographic appearance of thickened bronchial walls, bronchiectasis, bronchiolitis, or acinar consolidation. (05 Mar 2000) |
| alveolar pattern | Cloudy to dense opacities, obscuring vascular markings, on chest radiographs. Synonym: airspace-filling pattern. (05 Mar 2000) |
| A-pattern strabismus | Strabismus in which esotropia is more marked in looking upward than downward, strabismus in which exotropia is more marked on looking downward than upward. Synonym: A-pattern strabismus. (05 Mar 2000) |
| axial pattern flap | A flap that includes a direct specific artery within its longitudinal axis. Synonym: arterial flap. (05 Mar 2000) |
| ballerina-foot pattern | A vigorous posteromedial contraction of the left ventricle coupled with convexity anteriorly sometimes resulting from poor contraction of the opposing anterior wall; it is the most frequent dyssynergy observed in the prolapsed mitral valve leaflet syndrome (even with a normal anterior wall) and produces a configuration of angiographic dye in the right anterior oblique projection resembling a ballerina's foot; sometimes called dancer's foot malformation. (05 Mar 2000) |
| banding pattern | <genetics> Chromosomes stained with certain dyes, commonly quinacrine (Q banding) or Giemsa (G banding), show a pattern of transverse bands of light and heavy staining that is characteristic for the individual chromosome. The basis of the differential staining, which is the same in most tissues, is not understood: each band represents 5-10% of the length, about 10exp7 base pairs, although this is not true for polytene chromosomes in Drosophila that show more than 4000 bands. (18 Nov 1997) |
| butterfly pattern | Bilateral, symmetric, pulmonary alveolar opacities sparing the periphery, on chest radiographs; usually caused by pulmonary oedema. (05 Mar 2000) |