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carbamoyl The acyl radical, NH2-CO-, the transfer of which plays an important role in certain biochemical reactions; e.g., in the urea cycle, via carbamoyl phosphate.
(05 Mar 2000)
carbamoyl phosphate H2NCO-OPO32-;a reactive intermediate capable of transferring its carbamoyl group (H2NCO-) to an acceptor molecule, forming citrulline from ornithine in the urea cycle, and ureidosuccinic acid from aspartic acid in pyrimidine ring formation.
(05 Mar 2000)
carbamoyl-phosphate synthase (ammonia) <enzyme> An enzyme that catalyses the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle.
Chemical name: Carbon dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
Registry number: EC 6.3.4.16
(12 Dec 1998)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) <enzyme> An enzyme that catalyses the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines.
Chemical name: Carbon dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
Registry number: EC 6.3.5.5
(12 Dec 1998)
carbamoyl phosphate synthetase A phosphotransferase catalyzing the formation of carbamoyl phosphate. There are two significant isozymes. Carbomoyl phosphate synthetase I is a mitochondrial enzyme that catalyses the reaction of 2ATP, NH3, CO2, and H2O to carbamoyl phosphate, 2ADP, and Pi. It is activated by N-acetylglutamate and participates in urea biosynthesis.
A deficiency of carbamoyl phosphate synthetase I can result in hyperammonaemia. Carbamoyl phosphate synthetase II is a cytosolic enzyme that, under physiological conditions, uses l-glutamine as the nitrogen source (producing l-glutamate) instead of NH3, is not activated by N-acetylglutamate, and is found in pyrimidine biosynthesis.
(05 Mar 2000)
carboxyl and carbamoyl transferases <enzyme> A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- groups.
Registry number: EC 2.1.3
(12 Dec 1998)
N-carbamoyl-D-amino acid amidohydrolase <enzyme> From comamonas sp.e222c; mw 120 kD; hydrolyzes d-enantiomers of various n-carbamoyl-d-amino acids to d-amino acids, ammonia and co2; sensitive to thiol reagents; does not require metal ions
Registry number: EC 3.5.1.-
Synonym: caa-amidohydrolase, carbamoyl d-aa amidohyrolase
(26 Jun 1999)
1-carbamoyl-L-amino acid amidohydrolase <enzyme> From bacillus stearothermophilus; amino acid sequence given in first source
Registry number: EC 3.5.1.-
Synonym: carbamoyl l-aa amidohydrolase, n-carbamyl-l-amino acid amidohydrolase
(26 Jun 1999)
ABO blood group <haematology> The major human blood type system which describes the oligosaccharide glycoprotein antigens found on the surface of human blood cells.
According to the type of antigen present, a person may be assigned a blood type of A, B, AB or O. A second type of antigen, the Rh factor, renders a positive or negative blood type. The ABO blood group system is important because it determines who can donate blood to or accept blood from whom.
Type A or AB blood will cause an immune reaction in people with type B blood and type B and AB blood will cause a reaction in people with type A blood.
Conversely, type O blood has no A or B antigens, so people with type O blood are universal donors.
And since AB blood already produces both antigens, people who are type AB can accept any of the other blood types without suffering an immune reaction.
(04 Jul 1999)
actinobacteria group A group of gram-positive, heterogeneous bacteria. This group encompasses a range of morphologically, physiologically, and chemically different organisms and includes bacteria that form cocci, short rods, irregular rods, and mycelia that fragment.
(12 Dec 1998)
alkyl group <chemistry> A funtional group on an organic molecule which is derived from an alkane which has lost a hydrogen atom.
(13 Nov 1997)
aluminum group Aluminum, boron, gallium, indium, and thallium.
(05 Mar 2000)
amino group <biochemistry> An -NH2 group. Organic compounds which have this group are called amines.
(09 Oct 1997)
anterior group of axillary lymph nodes Lymph nodes located along the lateral thoracic vein; they receive the drainage of the pectoral region, including most of the drainage of the breast.
Synonym: nodi lymphatici axillaris pectorales, anterior group of axillary lymph nodes.
(05 Mar 2000)
apical group of axillary lymph nodes The group of lymph node's located at the apex of the axillary fossa that receive lymphatic drainage from other groups of axillary node's and then drain in turn into the subclavian lymphatic trunk.
Synonym: nodi lymphatici axillares apicales.
(05 Mar 2000)
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