| EC | effective concentration; ejection click; electrochemical; electron capture; embryonal carcinoma; eme... |
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| ECC | electrocorticogram, electrocorticography; electronic claim capture; embryonal cell carcinoma; emerge... |
| ECD | ectrodactyly; electrochemical detector; electron capture detector; endocardial cushion defect; enzym... |
| HCM | Hypertrophic Cardio-Myopathy = HCMP |
| LIMM | lethal infantile mitochondrial myopathy |
| CNM | Centronuclear myopathy |
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| MM | Miyoshi myopathy |
| MTM1 | Myotubular myopathy |
| PROMM | Proximal myotonic myopathy |
| IIM | idiopathic inflammatory myopathy |
| carcinomatous myopathy | <syndrome> A condition characterised by muscle weakness that is similar to the symptoms of myasthenia gravis. For this reason, it has been referred to as myasthenic syndrome. This disorder is caused by an insufficient release of neurotransmitter (acetylcholine) by the nerve cells. Unlike myasthenia gravis, as muscle contractions are continued, strength will increase. The cause of Lambert-Eaton syndrome is unknown, but is usually associated with small cell carcinoma of the lung or an autoimmune illness. (27 Sep 1997) |
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| centronuclear myopathy | Slowly progressive generalised muscle weakness and atrophy beginning in childhood; on biopsy of skeletal muscle, the nuclei of most muscle fibres are seen to be located near the centre of a small fibre (the normal position for a 10-week embryo) rather than at the periphery of the fibre; familial incidence. Autosomal dominant recessive and X-linked [310400] forms occur. Synonym: myotubular myopathy. Distal myopathy, myopathy affecting predominantly the distal portions of the limbs; onset is usually after age 40, with weakness and wasting of small muscles of the hands; The infantile form and the Swedish later-onset are autosomal dominant and there is a Japanese late-onset type that is recessive. Minicore-multicore myopathy, an uncommon nonprogressive myopathy with early onset, proximal weakness, and hypotonia. Muscle fibres show focal defects of oxidative and myofibrillar adenosine triphosphatase enzymes with disorganization of myofibril ultrastructure. Mitochondrial myopathy, weakness and hypotonia of muscles, primarily those of the neck, shoulder, and pelvic girdles, with onset in infancy or childhood; on biopsy, giant, bizarre mitochondria are seen located between muscle fibrils just beneath the sarcolemma. The dominant form is due to deletion of mitochondrial DNA and the recessive form is due to a complex deficiency. (05 Mar 2000) |
| rod myopathy | A congenital myofibrillar abnormality in which small threadlike or rod-shaped bodies are scattered through the muscle fibres. It is marked by hypotonia and proximal muscle weakness. It is also called rod myopathy with reference to the threadlike (greek nema, thread) rods or myofibrils (latin fibrilla, a little fibre or threadlike structure). (12 Dec 1998) |
| myopathy | <neurology> Any disease of a muscle. Origin: Gr. Pathos = disease (18 Nov 1997) |
| myotubular myopathy | Slowly progressive generalised muscle weakness and atrophy beginning in childhood; on biopsy of skeletal muscle, the nuclei of most muscle fibres are seen to be located near the centre of a small fibre (the normal position for a 10-week embryo) rather than at the periphery of the fibre; familial incidence. Autosomal dominant recessive and X-linked [310400] forms occur. Synonym: myotubular myopathy. Distal myopathy, myopathy affecting predominantly the distal portions of the limbs; onset is usually after age 40, with weakness and wasting of small muscles of the hands; The infantile form and the Swedish later-onset are autosomal dominant and there is a Japanese late-onset type that is recessive. Minicore-multicore myopathy, an uncommon nonprogressive myopathy with early onset, proximal weakness, and hypotonia. Muscle fibres show focal defects of oxidative and myofibrillar adenosine triphosphatase enzymes with disorganization of myofibril ultrastructure. Mitochondrial myopathy, weakness and hypotonia of muscles, primarily those of the neck, shoulder, and pelvic girdles, with onset in infancy or childhood; on biopsy, giant, bizarre mitochondria are seen located between muscle fibrils just beneath the sarcolemma. The dominant form is due to deletion of mitochondrial DNA and the recessive form is due to a complex deficiency. (05 Mar 2000) |
| nemaline myopathy | A congenital myofibrillar abnormality in which small threadlike or rod-shaped bodies are scattered through the muscle fibres. It is marked by hypotonia and proximal muscle weakness. It is also called rod myopathy with reference to the threadlike (greek nema, thread) rods or myofibrils (latin fibrilla, a little fibre or threadlike structure). (12 Dec 1998) |
| ocular myopathy | A specific type of slowly worsening weakness of the ocular muscles, usually associated with a pigmentary retinopathy. See: Kearns-Sayre syndrome, oculopharyngeal dystrophy. Synonym: ocular myopathy. (05 Mar 2000) |
| thyrotoxic myopathy | Extreme muscular weakness in severe thyrotoxicosis affecting muscles of limbs and trunk as well as those used in speech and swallowing. (05 Mar 2000) |
| atrial capture beat | The cardiac cycle resulting when, after a period of A-V dissociation, the atria regain control of the ventricles; atrial depolarisation due to retrograde transmission from a ventricular ectopic beat or an electronically paced ventricular impulse. (05 Mar 2000) |
| boron neutron capture therapy | A technique for the treatment of neoplasms, especially gliomas and melanomas in which boron-10, an isotope, is introduced into the target cells followed by irradiation with thermal neutrons. (12 Dec 1998) |
| capture | Catching and holding a particle or an electrical impulse originating elsewhere. Origin: L. Capio, pp. -tus, to take, seise Atrial capture, control of the atria for one or more beats after a period of independent beating, as in complete A-V block or in junctional or ventricular ectopic beats or tachycardias by a retrograde impulse. Electron capture, a mode of radioactive disintegration, in which an orbital electron, usually from the K shell, is captured by the nucleus, converting a proton into a neutron with ejection of a neutrino and emission of a gamma ray, and emission of characteristic X-rays as the missing K-shell electron is replaced. Synonym: K capture. (05 Mar 2000) |
| capture-recapture method | Originally, a technique developed by biologists to track wild animal populations; now adapted for epidemiological studies of elusive human populations (e.g., prostitutes, teen runaways, IV drug users).By comparing data from several independent overlapping sample frames, it is possible to adjust for missing cases and to generate estimates of the prevalence of a given condition, for example, AIDS infection. (05 Mar 2000) |
| ventricular capture | Capture of the ventricle(s) by an impulse arising in the atria or A-V junction. (05 Mar 2000) |
| neutron capture therapy | A technique for the treatment of neoplasms in which an isotope is introduced into target cells followed by irradiation with thermal neutrons. (12 Dec 1998) |
| IgM antibody capture ELISA | Developed to impart significant improvement in assay specificity to indirect ELISA procedures for IgM isotype antibodies. Solid-phase support (usually microtitre plate wells) are coated with anti-human IgM antibodies capable of binding all IgM isotype antibodies present in the specimen. Reagent antigen is then added, followed by enzyme-labelled antigen-specific antibodies. If IgM antibodies specific for the antigen in question are present, the "sandwich" complex will result in enzymatic colour-change proportional to the concentration of IgM-specific antibody present. This technique appears to be the method of choice in many highly specific and more sensitive assays for IgM infectious disease antibodies. Acronym: MAC ELISA (05 Mar 2000) |
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