| cache | An obsolete device consisting of a lead cone covered with several layers of paper, having a mica window at the bottom, used as an applicator in radiotherapy, the radium or other radioactive substance being at the apex of the cone and filters being placed below as required. Origin: Fr. Hidden, covered (05 Mar 2000) |
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| cachectic | Relating to or suffering from cachexia. (05 Mar 2000) |
| cachectic diarrhoea | Diarrhoea occurring in patients with severe wasting. Usually due to underlying gastrointestinal disease. (05 Mar 2000) |
| cachectic endocarditis | Verrucous endocardial lesions occurring in the terminal stages of many chronic infectious and wasting diseases. Synonym: abacterial thrombotic endocarditis, cachectic endocarditis, terminal endocarditis, thromboendocarditis. (05 Mar 2000) |
| cachectic fever | A chronic disease, occurring in India, Assam, China, the area formerly known as the Mediterranean littoral areas, the Middle East, India, Pakistan, China, South and Central America, Asia, Africa caused by Leishmania donovani and transmitted by the bite of an appropriate species of sandfly of the genus Phlebotomus or Lutzomyia; the organisms grow and multiply in macrophages, eventually causing them to burst and liberate amastigote parasites which then invade other macrophages; proliferation of macrophages in the bone marrow causes crowding out of erythroid and myeloid elements, resulting in leukopenia, and anaemia, splenomegaly, and hepatomegaly which are characteristic, along with enlargement of lymph nodes; fever, fatigue, malaise, and secondary infections also occur; different strains of leishmaniasis donovani occur; leishmaniasis infantum in Eurasia, leishmaniasis chagasi in Latin America. Synonym: Assam fever, black sickness, Burdwan fever, cachectic fever, Dumdum fever, kala azar, tropical splenomegaly. (05 Mar 2000) |
| cachectic oedema | Oedema occurring in diseases characterised by wasting and hypoproteinaemia; due to low plasma oncotic pressure. Synonym: marantic oedema. (05 Mar 2000) |
| cachectic pallor | 1. Pallor associated with hippocratic facies, emaciation, and weakness, often heralding a moribund state. Synonym: cachectic pallor, achromia. Origin: G. Achromos, colourless (05 Mar 2000) |
| cachectin | <protein> Protein produced by macrophages that is responsible for the wasting (cachexia) associated with some tumours. Now known to be identical to tumour necrosis factor (TNF). Has three 17 kD sub units, all derived from a single highly conserved gene. (18 Nov 1997) |
| cachet | A seal-shaped capsule or wafer for enclosing powders of disagreeable taste. Origin: Fr. A seal (05 Mar 2000) |
| cachexia | <oncology> A profound and marked state of constitutional disorder, general ill health and malnutrition. Origin: Gr. Hexis = habit (18 Nov 1997) |
| cachexia aphthosa | <gastroenterology> An inherited disease where the intestinal lining is inflamed in response to the ingestion of a protein known as gluten. Gluten is present in many grains including rye, oats, barley and triticale. Symptoms in infants include diarrhoea, slow growth, bloody stools, weight loss, vomiting and clay-coloured stools. Symptoms in adults include abdominal distention, abdominal pain, fatigue, weight loss, bone pain and bone tenderness. Treatment involves the life-long avoidance of gluten. (04 Mar 1998) |
| cachexia aquosa | An edematous form of ancylostomiasis. Diabetic neuropathic cachexia, a clinical syndrome seen almost exclusively in elderly diabetic males, consisting of the rather sudden onset of severe limb pain, marked weight loss, depression, and impotence. These patients appear to have a combination of a severe diabetic polyneuropathy, diffuse bilateral diabetic polyradiculopathy, and diabetic autonomic neuropathy. (05 Mar 2000) |
| cachexia hypophyseopriva | A condition following total removal of the hypophysis cerebri resulting in panhypopituitarism marked by a fall of body temperature, electrolyte imbalance, and hypoglycaemia, followed by coma and death. (05 Mar 2000) |
| cachexia strumipriva | Signs and symptoms of hypothyroidism (with or without myxoedema) resulting from the loss of thyroid tissue, either from surgery, radiotherapy, or disease. Synonym: cachexia strumipriva, cachexia thyroidea. (05 Mar 2000) |
| cachexia thyroidea | Signs and symptoms of hypothyroidism (with or without myxoedema) resulting from the loss of thyroid tissue, either from surgery, radiotherapy, or disease. Synonym: cachexia strumipriva, cachexia thyroidea. (05 Mar 2000) |