| CNP | community nurse practitioner; continuous negative pressure; cranial nerve palsy; 2',3'-cyclic nucleo... |
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| PAF | paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl... |
| PDEB | phosphodiesterase beta |
| PDEG | phosphodiesterase gamma |
| PDIE | phosphodiesterase |
| cAMP PDE | cAMP phosphodiesterase |
|---|---|
| cAMP-PDE | Cyclic AMP-phosphodiesterase |
| 8 Br-cAMP | 8 Bromo-cAMP |
| CPT-cAMP | 8-(4-Chlorophenylthio)-cAMP |
| 8-Cl-cAMP | 8-Chloro-cAMP |
| cAMP phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
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| cAMP | <molecular biology> 3'5' cyclic ester of AMP. The first second messenger hormone signalling system to be characterised. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). CAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5'AMP. Also functions as an extracellular morphogen for some slime moulds. (18 Nov 1997) |
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| CAMP factor | A test to identify Group B beta-streptococci based on their formation of a substance (CAMP factor) that enlarges the area of haemolysis formed by streptococcal beta-haemolysin. Origin: Christie, Atkins, and Munch-Petersen, developers of the t. (05 Mar 2000) |
| camp fever | <disease, microbiology> An acute infectious disease characterised by high fever, a skin eruption and severe headache. In the past, typhus has been a disease of war, famine or catastrophe, being spread by lice, ticks or fleas. The infecting organism is Rickettsia prowazekii, sensitive to sulpha drugs or tetracycline. (27 Sep 1997) |
| camp hospital | A hospital unit located in a military or recreational encampment; usually of small size and limited facilities, for immediate care of illnesses and injuries. Synonym: camp hospital. (05 Mar 2000) |
| cAMP receptor protein | catabolite (gene) activator protein |
| CAMP test | A test to identify Group B beta-streptococci based on their formation of a substance (CAMP factor) that enlarges the area of haemolysis formed by streptococcal beta-haemolysin. Origin: Christie, Atkins, and Munch-Petersen, developers of the t. (05 Mar 2000) |
| adenosine 3',5'-cyclic phosphate phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
| alkylglycerophosphoethanolamine phosphodiesterase | <enzyme> From microsomal preparations of rabbit kidney medulla; hydrolyzes choline moiety from lyso-paf to form 1-alkyl-2-lysoglycerophosphate in rat brain and other tissue; only lysoglycerophospholipids with ether linkages at the sn-1 position serve as substrates; acyl analogs are not utilised; requires magnesium Registry number: EC 3.1.4.39 Synonym: lysophospholipase d (26 Jun 1999) |
| calcium-calmodulin-dependent phosphodiesterase | <enzyme> Hydrolyzes both cgmp and camp; induced during mitogenesis Registry number: EC 3.1.4.- Synonym: ca-cam-phosphodiesterase, calmodulin-dependent cgmp phosphodiesterase (26 Jun 1999) |
| gamma subunit, cGMP phosphodiesterase | <enzyme> Isolated from canine retinal rod photoreceptor cells; genbank u49359 Registry number: EC 3.1.14.- Synonym: pde-gamma, pdegamma, cgmp-pde gamma subunit (26 Jun 1999) |
| PDE4D3 phosphodiesterase | <enzyme> One of three variants encoded by pde4d gene; this form is expressed in rat thyroid cells Registry number: EC 3.1.4.- (26 Jun 1999) |
| glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase | <enzyme> Removes the glucose-1-phosphate from glc-alpha-1-p-6-mannose residues in glycoproteins as a unit; pH optimum 7.5 Registry number: EC 3.1.4.51 Synonym: ag1p phosphodiesterase, alpha-glucose-1-phosphate phosphodiesterase (26 Jun 1999) |
| glycerophosphodiester phosphodiesterase | <enzyme> E coli enzyme; acts on variety of substrates to give glycerol-3-phosphate plus an alcohol, such as ethanolamine, choline, glycerol or glycerophosphoglycerol Registry number: EC 3.1.4.46 Synonym: gpde-phosphodiesterase, glycerophosphosphoryl diester phosphodiesterase (26 Jun 1999) |
| phosphodiesterase | <enzyme> An enzyme that cleaves phosphodiesters to give a phosphomonoester and a free hydroxyl group. Examples include RNase, DNase, phospholipases C and D and the enzymes that convert cyclic nucleotides to the monoester forms. In casual usage the cAMP phosphodiesterase is usually meant. (18 Nov 1997) |
| phosphodiesterase inhibitors | Compounds which inhibit or antagonise the biosynthesis or actions of phosphodiesterases. (12 Dec 1998) |
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