| bufanolide | The fundamental steroid lactone of several vegetable (e.g., squill) and animal (e.g., toad) venoms or toxins; also found in the form of glycosides in plants (e.g., digitalis). The steroid is essentially a 5b-androstane, with a 14b H. The lactone at C-17 is structurally related to the -CH(CH3)CH2CH2CH3 radical attached to C-17 in the cholanes, and is in the same configuration as that of cholesterol (i.e., 20R); in some species, bufanolide is formed from cholesterol. Various bufanolide derivatives having unsaturation in the lactone ring (20,22) or elsewhere are known as (05 Mar 2000) |
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| bufanolides | Steroids derived from various bufo species and often possessing cardiotonic properties. (12 Dec 1998) |