| broad beta disease | Hyperlipoproteinaemia characterised by increased plasma levels of LDL, beta-lipoproteins, pre-beta-lipoproteins, cholesterol, phospholipids, and triglycerides; hypertriglyceridemia induced by a high carbohydrate diet, and glucose tolerance is abnormal; frequent eruptive xanthomas and atheromatosis, particularly coronary artery disease; biochemical defect lies in apolipoproteins; there are many varieties. Synonym: carbohydrate-induced hyperlipaemia, dysbetalipoproteinaemia, familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemia, familial hypercholesterolaemia with hyperlipaemia. (05 Mar 2000) |
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| broad church | A portion of the Church of England, consisting of persons who claim to hold a position, in respect to doctrine and fellowship, intermediate between the High Church party and the Low Church, or evangelical, party. The term has been applied to otherbodies of men holding liberal or comprehensive views of Christian doctrine and fellowship. "Side by side with these various shades of High and Low Church, another party of a different character has always existed in the Church of England. It is called by different names: Moderate, Catholic, or Broad Church, by its friends; Latitudinarian or Indifferent, by its enemies. Its distinctive character is the desire of comprehension. Its watch words are charity and toleration." (Conybeare) Source: Websters Dictionary (01 Mar 1998) |
| broad fascia | The strong deep fascia of the thigh, enveloping the muscles of the thigh and thickened laterally as the iliotibial track. Synonym: fascia lata, broad fascia. (05 Mar 2000) |
| broad-leafed | Having broad, or relatively broad, leaves. Source: Websters Dictionary (01 Mar 1998) |
| broad-leaved | Having broad, or relatively broad, leaves. Source: Websters Dictionary (01 Mar 1998) |
| broad ligament | <anatomy> A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. (12 Dec 1998) |
| broad ligament of the uterus | The peritoneal fold passing from the lateral margin of the uterus to the wall of the pelvis on either side, and in so doing also ensheathing the ovaries and uterine tubes. Synonym: ligamentum latum uteri. (05 Mar 2000) |
| broad spectrum | <pharmacology> Often used to describe an antibiotic that is effective against a wide range of microorganisms. (13 Nov 1997) |
| broad spectrum antibiotic | An antibiotic having a wide range of activity against both Gram-positive and Gram-negative organisms. (05 Mar 2000) |
| hernia of the broad ligament of the uterus | A coil of intestine contained in a pouch projecting into the substance of the broad ligament. (05 Mar 2000) |
| Aarskog-Scott syndrome | A syndrome of ocular hypertelorism, anteverted nostrils, broad upper lip, saddle-bag scrotum, and laxity of ligaments resulting in genu recurvatum, flat feet, and hyperextensible fingers; X-linked and autosomal dominant forms. Synonym: Aarskog-Scott syndrome. (05 Mar 2000) |
| Aarskog syndrome | <syndrome> Grier et al. (1983) reported father and 2 sons with typical Aarskog syndrome, including short stature, hypertelorism, and shawl scrotum. They tabulated the findings in 82 previous cases. X-linked recessive inheritance has been repeatedly suggested. The family reported by Welch (1974) had affected males in 3 consecutive generations. Thus, there is either genetic heterogeneity or this is an autosomal dominant with strong sex-influence and possibly ascertainment bias resulting from use of the shawl scrotum as a main criterion. Stretchable skin was present in the cases of Grier et al. (1983). Teebi et al. (1993) reported the case of an affected mother and 4 sons (including a pair of monozygotic twins) by 2 different husbands. They suggested that the manifestations were as severe in the mother as in the sons and that this suggested autosomal dominant inheritance. Actually, the mother seemed less severely affected, compatible with X-linked inheritance. Clinical signs: Mild to moderate short stature,normocephaly, Widow's peak hair, maxillary hypoplasia, broad nasal bridge, anteverted nostrils, long philtrum, broad upper lip, curved linear dimple below the lower lip, hypertelorism, ptosis, down-slanted palpebral fissures, ophthalmoplegia, strabismus, hyperopic astigmatism, large cornea, floppy ears, lop-ears,cleft lip/palate, shawl scrotum, saddle-bag scrotum, cryptorchidism, brachydactyly, digital contractures, clinodactyly, mild syndactyly, transverse palmar crease, lymphoedema of the feet, ligamentous laxity, osteochondritis dissecans, proximal finger joint hyperextensibility, flexed distal finger joints, genu recurvatum, flat feet, stretchable skin, cervical spine hypermobility, odontoid anomaly, macrocytic anaemia, hemochromatosis, hepatomegaly, portal cirrhosis, imperforate anus, rectoperineal fistula, interstitial pulmonary disease, sternal deformity. Inheritance: Sex-influenced autosomal dominant form, also X-linked form. (05 Aug 1998) |
| abdominal muscle deficiency syndrome | <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear. (05 Mar 2000) |
| abstinence syndrome | <syndrome> A constellation of physiologic changes undergone by persons or animals who have become physically dependent on a drug or chemical due to prolonged use at elevated doses, but who are abruptly deprived of that substance. The abstinence syndrome varies with the drug to which dependence has developed. Generally the effects observed are in an opposite direction from those produced by the drug; e.g., the withdrawal syndrome from central nervous system depressants such as barbiturates and benzodiazepines consists of insomnia, restlessness, tremulousness, hallucinations, and, in the extreme, tonic-clonic convulsions which may prove fatal. The onset time and severity of the abstinence syndrome depend upon how rapidly the drug disappears from the body. (05 Mar 2000) |
| Achard syndrome | <syndrome> Arachnodactyly with small receding mandible, broad skull, and joint laxity limited to the hands and feet; genetics unclear. (05 Mar 2000) |