| bone marrow | <haematology> The soft, spongy tissue found in the centre of most large bones that produces the cellular components of blood: white cells, red cells and platelets (haemopoiesis). It is also the most radiation sensitive tissue of the body. (12 May 1997) |
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| bone marrow aspirate | <procedure> A small volume of bone marrow removed under local or general anaesthetic from either the hip bone (pelvis) or breast bone (sternum). The cells in the sample can then be examined under the microscope to identify any abnormality in the developing blood cells. (13 Nov 1997) |
| bone marrow aspiration | <procedure> Procedure used to remove a sample of bone marrow, usually from the rear hip bone, for examination under the microscope. (16 Dec 1997) |
| bone marrow biopsy | <procedure> A test involving the insertion of a thin needle into the breastbone or more commonly, the hip, in order to aspirate a sample of the marrow. A small piece of cortical bone may also be obtained for biopsy. Anaemia of unknown cause is often investigated using this test. (27 Sep 1997) |
| bone marrow biopsy and aspiration | <procedure> A procedure in which a needle is inserted into the centre of a bone, usually the hip, to remove a small amount of bone marrow for microscopic examination. (09 Oct 1997) |
| bone marrow cells | The fat cells (adipocytes), large nucleated cells or myelocytes, and giant cells called megakaryocytes, filling the meshes making up the bone marrow, a meshwork of connective tissue containing branching fibres. (12 Dec 1998) |
| bone marrow dose | The cumulative dose to the blood-forming organ from therapeutic or nuclear fallout irradiation; the presumed leukemogenic dose. (05 Mar 2000) |
| bone marrow embolism | Obstruction of a vessel by bone marrow, usually following fracture of a bone. (05 Mar 2000) |
| bone marrow examination | Removal of bone marrow and evaluation of its histologic picture. (12 Dec 1998) |
| bone marrow harvesting | <procedure> A medical procedure which involves collecting healthy bone marrow which willbe stored and used in a future bone marrow transplant. (09 Oct 1997) |
| bone marrow neoplasms | Neoplasms located in the bone marrow. They are differentiated from neoplasms composed of bone marrow cells, such as myeloma. most bone marrow neoplasms are metastatic. (12 Dec 1998) |
| bone marrow purging | Techniques for the removal of subpopulations of cells (usually residual tumour cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic bone marrow transplantation. (12 Dec 1998) |
| bone marrow suppression | <oncology, pharmacology> A side effect of many anticancer and antiviral drugs, including AZT. Bone marrow suppression leads to a decrease in white blood cells, red blood cells and platelets. Such reductions in turn result in anaemia, bacterial infections and spontaneous or excess bleeding. (09 Oct 1997) |
| bone marrow transplant | <procedure> A procedure in which a section of bone marrow is taken from one person and transplanted into another. It is used to replace bone marrow that has been damaged or diseased. It can be a treatment option in leukaemia. Acronym: BMT (16 Dec 1997) |
| bone marrow transplantation | <oncology, procedure> Treatment in which healthy bone marrow replaces bone marrow that has been affected by a disease or by treatment for a disease. Acronym: BMT (12 May 1997) |
| allogeneic bone marrow transplant | <haematology, procedure> A bone marrow transplant using marrow collected from a matched healthy donor, usually a brother or sister. The risks associated with the transplant increase with age and 50 years of age is generally regarded as the upper limit. (13 Nov 1997) |
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| autologous bone marrow transplant | <haematology, procedure> A process in which a patients healthy bone marrow is withdrawn and preserved. It is later injected back into the patient to replace bone marrow damaged by high doses of radiation therapy. It can then produce healthy blood cells. This treatment is used to offset the detrimental effects of high-dose radiation used in certain types of cancer. (31 Dec 1997) |
| red bone marrow | Bone marrow in which the meshes contain the developmental stages of erythrocytes, leukocytes, and megakaryocytes. Synonym: medulla ossium rubra. (05 Mar 2000) |
| syngeneic bone marrow transplant | <haematology, oncology, procedure> Transplant in which an identical twin is the bone marrow donor. (19 Jan 1998) |
| yellow bone marrow | Bone marrow in which the meshes of the reticular network are filled with fat. Synonym: medulla ossium flava. (05 Mar 2000) |
| marrow | 1. <anatomy> The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in colour. 2. The essence; the best part. "It takes from our achievements . . . The pith and marrow of our attribute." (Shak) 3. [OE. Maru, maro; perh. A different word; cf. Gael. Maraon together] One of a pair; a match; a companion; an intimate associate. "Chopping and changing I can not commend, With thief or his marrow, for fear of ill end. <botany>" (Tusser) Marrow squash See Spinal cord, under Spinal. Origin: OE. Marou, mary, maruh, AS. Mearg, mearh; akin to OS. Marg, D. Merg, G. Mark, OHG. Marg, marag, Icel. Mergr, Sw. Merg, Dan. Marv, Skr. Majjan; cf. Skr. Majj to sink, L. Mergere. Cf. Merge. Source: Websters Dictionary (01 Mar 1998) |
| marrow canal | The chamber of the dental pulp lying within the root portion of a tooth. Synonym: canalis radicis dentis, marrow canal, pulp canal. (05 Mar 2000) |
| marrow cell | Any cell of bone marrow, especially haemopoietic cell's. (05 Mar 2000) |
| marrow-lymph gland | A type of haemal node, resembling the bone marrow in structure and probable function. (05 Mar 2000) |
| spinal marrow | <anatomy> Elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. (18 Nov 1997) |
| osteoporotic marrow defect | Focal osteoporotic bone marrow defect of the jaw; a focal radiolucent defect composed of normal marrow. (05 Mar 2000) |
| bone within a bone | <radiology> STOP heavy metal, S: sickle cell disease, T: Thorotrast, O: osteopetrosis, P: Paget's disease, heavy metals, hypervitaminosis D (12 Dec 1998) |
| acute reflex bone atrophy | Atrophy of bones, commonly of the carpal or tarsal bones, following a slight injury such as a sprain. See: causalgia, reflex sympathetic dystrophy. Synonym: acute reflex bone atrophy, posttraumatic osteoporosis, Sudeck's syndrome. Origin: L. English sweat (05 Mar 2000) |
| air-bone gap | The difference between the threshold for hearing acuity by bone conduction and by air conduction. (05 Mar 2000) |
| Albrecht's bone | A small bone between the basioccipital and basisphenoid. (05 Mar 2000) |