| bisphosphoglycerate mutase |
[EC 5.4.2.4] an enzyme of the isomerase class that catalyzes the interconversion of 1,3-bisphosphoglycerate and 2,3-bisphosphoglycerate; it requires Mg2+ as a cofactor and is more active in the presence of 3-phosphoglycerate. The reaction produces 2,3-bisphosphoglycerate necessary for glucose catabolism and for erythrocytic regulation of hemoglobin oxygen affinity. Deficient enzyme activity, an autosomal recessive trait, results in a form of hemolytic anemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|