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Birnaviridae the two-segmented double-stranded RNA viruses: a family of RNA viruses having a nonenveloped icosahedral virion 60 nm in diameter with 92 capsomers in a T = 9 arrangement. The genome consists of two segments of linear double-stranded RNA (MW 2.2–2.5 × 106 and 2.4–2.6 × 106, size of total genome about 6 kbp). Viruses contain five major structural polypeptides and are resistant to light and ultraviolet radiation, heat, lipid solvents, and trypsin. Replication and assembly occur in the cytoplasm; it includes Aquabirnavirus (infecting fish, mollusks, and crustaceans), Avibirnavirus (infecting birds), and Entomobirnavirus (infecting insects).
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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