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bicarbonate <chemistry> A carbonate in which but half the hydrogen of the acid is replaced by a positive element or radical, thus making the proportion of the acid to the positive or basic portion twice what it is in the normal carbonates; an acid carbonate; sometimes called supercarbonate.
They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
Pharmacological action: buffers.
(27 Jun 1999)
bicarbonate ATPase <enzyme> Anion sensitive
Registry number: EC 3.6.1.-
Synonym: hco(3)-atpase, atpase, bicarbonate, cl atpase, atpase, chloride, chloride-bicarbonate atpase, anion-sensitive atpase
(26 Jun 1999)
magnesium-bicarbonate ATPase <enzyme> Aspect of EC 3.6.1.3
Registry number: EC 3.6.1.-
Synonym: mg-hco3-atpase, atpase, magnesium-bicarbonate
(26 Jun 1999)
potassium bicarbonate KHCO3;used as a diuretic to decrease the acidity of the urine, and as an electrolyte replenisher.
(05 Mar 2000)
serum bicarbonate A measure of the bicarbonate level in the blood based on a venipuncture specimen. The serum carbon dioxide is one of the normally reported values in the electrolytes profile. Lower levels of carbon dioxide indicate an acidosis. The normal level is 20 to 29 mEq/L. Lower than normal levels can indicate diabetic ketoacidosis, lactic acidosis, alcoholic ketoacidosis, kidney disease, renal failure, diarrhoea, Addison's disease, ethylene glycol poisoning or methanol poisoning. Greater than normal levels can be seen with excessive vomiting, hyperaldosteronism and Cushing's syndrome.
(27 Sep 1997)
sodium bicarbonate <chemical> Carbonic acid monosodium salt (CHNaO3).
A white, crystalline powder that is used as an electrolyte replenisher and systemic alkaliser. It is applied topically in solution to wash the nose, mouth, or vagina, and as a cleansing enema.
Pharmacologic action: Acid neutralization.
Uses: Preexisting metabolic acidosis, hyperkalemia, tricyclic or phenobarbital overdose.
Dose in mEq: 0.3 * (base deficit) * (wt in kg).
Potential complications: Metabolic alkalosis, hypercarbia, hyperosmolar state.
Note: Since HCO3- does not cross cell membranes and CO2 does, the administration of bicarbonate may actually make tissues more acidotic.
Chemical name: Carbonic acid monosodium salt.
(12 Mar 2000)
buffer <biochemistry, chemistry> A system that acts to minimise the change in concentration of a specific chemical species in solution against addition or depletion of this species.
PH buffers: weak acids or weak bases in aqueous solution. The working range is given by pKa +/ 1.
Metal ion buffers: a metal ion chelator for example EDTA, partially saturated by the metal ion acts, as a buffer for the metal ion.
(18 Nov 1997)
buffer capacity <chemistry> The ability of a buffer solution to absorb added alkali or acid while maintaining the solution's pH.
(09 Oct 1997)
buffer index The power of a substance in solution to absorb acid or alkali without change in pH; this is highest at a pH value equal to the pKa value of the acid of the buffer pair.
See: buffer capacity.
Synonym: buffer index.
(05 Mar 2000)
buffer pair An acid and its conjugate base (anion).
(05 Mar 2000)
buffer value The power of a substance in solution to absorb acid or alkali without change in pH; this is highest at a pH value equal to the pKa value of the acid of the buffer pair.
See: buffer capacity.
Synonym: buffer index.
(05 Mar 2000)
buffer value of the blood The ability of the blood to compensate for additions of acid or alkali without disturbance of the pH.
(05 Mar 2000)
buffer zone <ecology> An area of land separating two distinct land uses that acts to soften or mitigate the effects of one land use on the other.
(09 Oct 1997)
riparian buffer Riparian areas that are managed to protect the aquatic and riparian ecosystem. A riparian buffer protects water quality and temperature, habitat along the banks, upland habitat for aquatic and riparian species, and some or all of the floodplain.
(05 Dec 1998)
secondary buffer See: Hamburger's law.
(05 Mar 2000)
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