| beta-lactam | <pharmacology> A class of broad spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins. (05 Mar 2000) |
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| beta-lactam resistance | Nonsusceptibility of an organism to the action of the beta-lactam antibiotics. (12 Dec 1998) |
| beta-lactamase | <enzyme> An enzyme produced by some bacteria, which causes the breakdown of the active form of some penicillin antibiotics, rendering them ineffective. It causes the hydrolysis of a beta-lactam (as penicillin to penicilloic acid); found in most strains of staphylococcus bacteria that are naturally resistant to penicillin. Synonym: cephalosporinase, penicillinase. (05 Mar 2000) |
| beta-lactamase inhibitor | <pharmacology> Drugs such as clavulanic acid, which are used to inhibit bacterial beta-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance. (05 Mar 2000) |
| beta-lactamases | <enzyme> Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins. Chemical name: beta-Lactamhydrolase Registry number: EC 3.5.2.6 (12 Dec 1998) |
Synonyms : beta Lactam Resistance, beta-Lactam Resistances
Synonyms : beta-Lactamase, beta Lactamase, beta Lactamases
Synonyms : beta Lactams
| beta-lactamase |
penicillinase: enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
Ãâó: wordnet.princeton.edu/perl/webwn
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| beta-lactam |
A beta-lactam (β-lactam) is a lactam with a heteroatomic ring structure, consisting of three carbon atoms and one nitrogen atom (Fig. 1). The beta-lactam ring is part of several antibiotics, such as penicillin, which are therefore also called beta-lactam antibiotics. These antibiotics work by inhibiting the bacterial cell wall synthesis. This has a lethal effect on bacteria, especially on Gram-positive ones. ...
Ãâó: en.wikipedia.org/wiki/Beta-lactam
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| beta-lactam antibiotic |
Any of the antimicrobial drugs, such as penicillins or cephalosporins, that kill germs by interfering with the synthesis of bacterial cell walls. SYN: beta-lactam.
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| beta-lactamase resistance |
The ability of microorganisms that produce the enzyme beta-lactamase, also called penicillinase, to resist the action of certain types of antibiotics, including some but not all forms of penicillin.
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| beta-lactamase resistant penicillin |
Synthetic penicillins that resist the action of the enzyme beta-lactamase, produced by some microorganisms. Bacteria that produce the enzyme are not susceptible to the action of non?beta-lactamase resistant pe
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| beta-lactam | enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic |
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