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beta-d-glucuronidase <enzyme> An enzyme catalyzing the hydrolysis of various beta-d-glucuronides, liberating free d-glucuronic acid and an alcohol; a deficiency of this enzyme is associated with Sly syndrome.
Synonym: glusulase, glycuronidase.
(05 Mar 2000)
beta-d-glucuronidase deficiency A rare deficiency of beta-d-glucuronidase; an autosomal recessive disorder with several allelic forms, characterised by abnormal mucopolysaccharide metabolism leading to progressive mental deterioration, splenic and hepatic enlargement, and dysostosis multiplex.
Synonym: mucopolysaccharidase.
(05 Mar 2000)
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