| beta-d-galactosidase | A sugar-splitting enzyme that catalyses the hydrolysis of lactose into d-glucose and d-galactose, and that of other beta-d-galactosides; it also catalyses galactotransferase reactions; a deficiency of beta-d -galactosidase leads to problems in the intestinal digestion of lactose; used in the production of milk products for adults who do not have the intestinal enzyme; a defect of one isozyme of beta-d-galactosidase is associated with Morquio's syndrome type B. Compare: lactase persistence, lactase restriction. Synonym: lactase. (05 Mar 2000) |
|---|---|
| beta-galactosidase | <enzyme> A group of enzymes that catalyses the hydrolysis of terminal, non-reducing beta-d-galactose residues in beta-galactosides. Chemical name: beta-D-Galactoside galactohydrolase Registry number: EC 3.2.1.23 (12 Dec 1998) |
| keratan-sulfate endo-1,4-beta-galactosidase | <enzyme> Do not confuse with EC 3.2.1.102 blood-group substance endo-1,4-beta-galactosidase which is also called in enzyme nomenclature endo-beta-galactosidase Registry number: EC 3.2.1.103 Synonym: keratanase, endo-beta-galactosidase (26 Jun 1999) |
| 4-methylumbelliferyl-beta-galactosidase | <enzyme> Non-specific brain enzyme; distinct from EC 3.2.1.46 Registry number: EC 3.2.1.- Synonym: 4-mub-galactosidase (26 Jun 1999) |
| alpha-d-galactosidase | <enzyme> An enzyme catalyzing the hydrolysis of alpha-d-galactosides to release free d-galactose. A deficiency of type A alpha-d-galactosidase is associated with Fabry's disease. Synonym: melibiase. (05 Mar 2000) |
| alpha-galactosidase | <enzyme> An enzyme that catalyses the hydrolysis of terminal, non-reducing alpha-d-galactose residues in alpha-galactosides including galactose oligosaccharides, galactomannans, and galactolipids. Chemical name: alpha-D-Galactoside galactohydrolase Registry number: EC 3.2.1.22 (12 Dec 1998) |
| b galactosidase | <enzyme> An enzyme that hydrolyzes the beta galactoside linkage in lactose-producing glucose and galactose; also hydrolyzes the chromogenic substrate IPTG (isopropylthiogalactoside) and thus is used as an indicator of fused genes and gene expression. (05 Mar 2000) |
| galactosidase | <enzyme> One of a class of enzymes which cuts the glycosidic bond between the sugar galactose and another sugar molecule (of a different type than galactose). There are two subclasses - the alpha galactosidases and beta galactosidases - which cuts the two types of glycosidic bonds (alpha and beta, respectively). (09 Oct 1997) |
| 4-methylumbelliferyl alpha-galactosidase | <enzyme> Aspect of EC 3.2.1.22, alpha-galactosidase Registry number: EC 3.2.1.- (26 Jun 1999) |
| androst-5-ene-3 beta,17 beta-diol | <chemical> An adrenal-derived oestrogenic metabolite of dhea. Evidence exist for its use as an endocrine regulator of immune response. Pharmacological action: anabolic steroids. Chemical name: Androst-5-ene-3,17-diol, (3beta,17beta)- (12 Dec 1998) |
| beta-1,3-galactosyl-0-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase | <enzyme> Capable of adding a glcnac residue to g1cnacman(3)g1cnac; from mung bean seedlings Registry number: EC 2.4.1.146 Synonym: n-acetylglucosaminyltransferase II, gal3-(glcnac6)galnac-mucin (glcnac--gal)3-glcnactransferase (26 Jun 1999) |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase | <enzyme> With EC 2.4.1.148 this is called beta6-glcnac-transferase b Registry number: EC 2.4.1.102 Synonym: gal3-galnac-mucin-6-glcnac transferase, udp-glcnac-gal1-3galnac-r-(glcnac to galnac)-beta1-6glcnac transferase, core 2 glcnac transferase, core 2-n-acetylglucosaminyltransferase, core 2 beta6-gn-t (26 Jun 1999) |
| beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase | <enzyme> Induced in preneoplastic stage of liver carcinogenesis promoted by orotic acid in rats; adds "bisecting n-acetylglucosaminyl residue in beta 1,4 linkage to the beta-linked mannose of the core of asparagine-linked oligosaccharides Registry number: EC 2.4.1.144 Synonym: n-acetylglucosaminyltransferase III, udpgnac-glycopeptide beta4-n-acetylglucosaminyl transferase III, udpgnac-magtransferase III, udp-n-acetylglucosamine-beta-d-mannoside beta-1,4-n-acetylglucosaminyltransferase III (26 Jun 1999) |
| beta-hydroxy-beta-methylglutaryl-CoA | -OOCCH2C(OH)(CH3)CH2COS-CoA;a key intermediate in the synthesis of ketone bodies and of steroids. Synonym: 3-hydroxy-3-methylglutaryl-CoA. Beta-hydroxy-beta-methylglutaryl-lyase, an enzyme, found primarily in liver and rumen epithelium that catalyses the formation of acetyl-CoA and acetoacetate from beta-hydroxy-beta-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis. Beta-hydroxy-beta-methylglutaryl-reductase, an enzyme that catalyses the rate-limiting step of cholesterol biosynthesis, beta-hydroxy-beta-methylglutaryl-CoA + 2NADPH + 2H+ → mevalonate + 2NADP+ + coenzyme A. Beta-hydroxy-beta-methylglutaryl-synthase, an enzyme in mitochondria that catalyses the reaction of acetyl-CoA with acetoacetyl-CoA and water to form beta-hydroxy-beta-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur. (05 Mar 2000) |
| beta-n-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase | <enzyme> An enzyme that catalyses the transfer of galactose from udp-galactose to a specific glycoprotein receptor, 2-acetamido-2-deoxy-d-glucosyl-glycopeptide, during glycopeptide synthesis. Chemical name: UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase Registry number: EC 2.4.1.38 (12 Dec 1998) |