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benzo(a)pyrene <chemical> A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
Pharmacological action: carcinogens, environmental pollutants, mutagens.
Chemical name: Benzo(a)pyrene
(12 Dec 1998)
benzo(a)pyrene-4,5-oxide hydratase <enzyme> Aspect of epoxide hydrolase, EC 3.3.2.3
Registry number: EC 3.3.2.-
(26 Jun 1999)
benzoate <chemistry> A salt formed by the union of benzoic acid with any salifiable base.
Origin: Cf. F. Benzoate.
(06 Aug 1998)
benzoate 1,2-dioxygenase <enzyme> Benzoate to catechol; prior to 1992 was EC 1.13.99.2
Registry number: EC 1.14.12.10
Synonym: benzoate hydroxylase
(26 Jun 1999)
benzoate coenzyme A ligase <enzyme> From rhodopseudomonas palustris; involved in anaerobic degradation of benzoate; high specificity for benzoate and fluorobenzoate
Registry number: EC 6.2.1.25
Synonym: benzoate-CoA ligase, benzoic acid coenzyme a ligase, benzoyl-CoA ligase, benzoyl CoA synthetase
(26 Jun 1999)
benzoate synthase <enzyme> Enzyme or system catalyzing synthesis of benzoate from cinnamate (75)
Registry number: EC 1.-
(26 Jun 1999)
benzoated Containing benzoic acid or a benzoate, usually sodium benzoate.
(05 Mar 2000)
benzocaine <chemical> 4-aminobenzoic acid ethyl ester. A surface anaesthetic that acts by preventing transmission of impulses along nerve fibres and at nerve endings. It is comparatively non-irritating and has low systemic toxicity.
Pharmacological action: anaesthetics, local.
Chemical name: Benzoic acid, 4-amino-, ethyl ester
(12 Dec 1998)
benzodiazepine <pharmacology> A class of drug widely used in medical practice as CNS depressants, for example diazepam (the tranquilliser Valium). Enhance the inhibitory action of GABA by modulating GABAA receptors.
(06 Aug 1998)
benzodiazepines A two-ring heterocyclic compound consisting of a benzene ring fused to a diazepine ring. Permitted is any degree of hydrogenation, any substituents and any h-isomer.
(12 Dec 1998)
benzoflavones <chemical> Organic compounds containing a benzene ring attached to a flavone group. Some of these are potent arylhydrocarbon hydroxylase inhibitors. They may also inhibit the binding of nucleic acids to benzopyrenes and related compounds. The designatin includes all isomers; the 7,8-isomer is most frequently encountered.
Pharmacological action: enzyme inhibitors.
(12 Dec 1998)
benzoic <chemistry> Pertaining to, or obtained from, benzoin. Benzoic acid, or flowers of benzoin, a peculiar vegetable acid, obtained from benzoin, and some other balsams, by sublimation or decoction.
It is also found in the urine of infants and herbivorous animals. It crystallizes in the form of white, satiny flakes; its odour is aromatic; its taste is pungent, and somewhat acidulous.
Benzoic aldehyde, oil of bitter almonds; the aldehyde, C6H5.CHO, is an intermediate in composition between benzoic or benzyl alcohol, and benzoic acid. It is a thin colourless liquid.
Structure: C6H5.CO2H
Origin: Cf. F. Benzoique.
(06 Aug 1998)
benzoic acid C6H5COOH;occurs naturally in gum benzoin; it is used as a food preservative, locally as a fungistatic, and orally as an antiseptic, diuretic, and expectorant. It is excreted rapidly as hippuric acid.
Synonym: benzoyl hydrate, flowers of benzoin.
(05 Mar 2000)
benzoic aldehyde C6H5CHO;an aldehyde produced artificially or obtained from oil of bitter almond, containing not less than 80% of benzaldehyde; a flavoring agent used in orally administered medicines.
Synonym: benzoic aldehyde.
(05 Mar 2000)
benzoin 1. A resinous substance, dry and brittle, obtained from the Styrax benzoin, a tree of Sumatra, Java, etc, having a fragrant odour, and slightly aromatic taste. It is used in the preparation of benzoic acid, in medicine, and as a perfume.
2. A white crystalline substance, C14H12O2, obtained from benzoic aldehyde and some other sources.
3. <botany> The spicebush (Lindera benzoin). Flowers of benzoin, benzoic acid. See Benzoic.
Source: Websters Dictionary
(01 Mar 1998)
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