| acute toxicity | <pharmacology> Illness resulting from a single dose or exposure to a toxic substance. Compare: chronic toxicity. (06 May 1997) |
|---|---|
| chronic toxicity | <pharmacology> Illness caused by repeated or long-term exposure to low doses of a toxic substance. Compare: acute toxicity. (09 Oct 1997) |
| digitalis toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| digoxin toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| drug toxicity | The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. (27 Sep 1997) |
| oxygen toxicity | A body disturbance resulting from breathing high partial pressures of oxygen; characterised by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation. Synonym: oxygen poisoning. (05 Mar 2000) |
| toxicity | The quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. (18 Nov 1997) |
| toxicity test | <investigation> Controlled laboratory test to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations. An acute toxicity test establishes the concentration required to kill a predetermined proportion of test organisms within a relatively short period of time, typically 4 days or less. A chronic toxicity test reveals the effects of a sublethal concentration applied throughout all or part of the life cycle. (12 Jan 1998) |
| toxicity tests | Tests that determine the toxicity of a substance. These include tests of clinical drugs, foods, environmental pollutants, etc. (12 Dec 1998) |
| ep toxicity | A test defined by the federal Environmental Protection Agency to check a substance for the presence of arsenic, barium, cadmium, chromium, lead, mercury, selenium, or silver. 40 CFR 261.24 defines the concentrations constituting hazardous waste and the test procedure. (05 Dec 1998) |