| autoimmune d. |
a disorder caused by an immune response directed against self antigens. Ideally there should be not only demonstrable circulating autoantibodies or cell-mediated immunity against autoantigens in conjunction with inflammatory lesions caused by immunologically competent cells or immune complexes in tissues containing the autoantigens but also clinical or experimental evidence that the autoimmune process is pathogenic not secondary to other tissue damage. In practice many diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis are often classified as autoimmune diseases although their pathogenesis is unclear.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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