asialoglycoprotein : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 2 페이지: 1

Asialoglycoprotein Receptor - 새창 A C-type lectin that is a cell surface receptor for ASIALOGLYCOPROTEINS. It is found primarily in the LIVER where it mediates the endocytosis of serum glycoproteins.
Synonyms : ASGP-R, Asialoorosomucoid Receptor, Asialoorosomucoid Receptors, Asialoorosomucoid-Binding Protein, Hepatic Asialoglycoprotein Receptor, Hepatic Lectin, Liver Carbohydrate-Binding Protein, Receptor, Asialoglycoprotein, Receptor, Asialoorosomucoid
Asialoglycoproteins - 새창 Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
Synonyms : Desialylated Glycoproteins, Glycoproteins, Desialylated