| aseptic necrosis | <orthopaedics, pathology> Condition in which poor blood supply to an area of bone leads to bone death. Also called avascular necrosis and osteonecrosis. (12 Dec 1998) |
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| epiphysial aseptic necrosis | Aseptic necrosis of bony epiphyses, probably due to ischemia; it may affect the upper end of the femur (Legg-Calve-Perthes disease), the tibial tubercle (Osgood-Schlatter disease), the tarsal navicular bone or the patella (Kohler's disease), the second metatarsal head (Freiberg's disease), vertebral bodies (Scheuermann's disease), or the capitellum of the humerus (Panner's disease). (05 Mar 2000) |
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| aseptic | <microbiology> Freedom from infection or septic material, sterile. (18 Nov 1997) |
| aseptic bursitis | Inflammation of a bursa that is not caused by infection. A bursa is a closed fluid-filled sac that functions as a gliding surface to reduce friction between tissues of the body. When the bursa becomes inflamed, the condition is known as bursitis. most commonly this is not an infectious condition (aseptic bursitis). (12 Dec 1998) |
| aseptic fever | Fever accompanied by malaise due to absorption of dead but not infected tissue following an injury. (05 Mar 2000) |
| aseptic meningitis | <neurology> A meningeal reaction in the cerebrospinal fluid sometimes occurring in the absence of an infecting organism. It can be due to a virus, foreign substance, diagnostic or therapeutic procedure, or to a tumour or a septic focus within the skull or spinal canal. <virology> When due to a virus, it is seen most often in those under 30 years of age. Peak time for infection is in late summer. Majority of cases are caused by the Coxsackie and echovirus. (21 Jun 1999) |
| aseptic surgery | The performance of an operation with sterilised hands, instruments, etc., and utilizing precautions against the introduction of infectious microorganisms from without. (05 Mar 2000) |
| aseptic technique | <procedure> A method used by microbiologists and clinicians to keep cultures, sterile instruments and media, and people free of microbial contamination. (09 Oct 1997) |
| bursitis, aseptic | A bursa is a closed fluid-filled sac that functions as a gliding surface to reduce friction between tissues of the body. When the bursa becomes inflamed, the condition is known as bursitis. most commonly this is not an infectious condition (aseptic bursitis). (12 Dec 1998) |
| acute tubular necrosis | <nephrology> A kidney disorder that results in damage to the renal tubule cells leading to acute renal failure. Acute tubular necrosis can result from any condition which deprives the kidney of oxygen (ischaemia). Acute tubular necrosis may occur as a complication of shock, trauma or sepsis. Conditions such as diabetes or liver disease can predispose people to the development of acute tubular necrosis. Certain medications (for example aminoglycosides, amphotericin B, cyclosporine) are known to cause acute tubular necrosis as a toxic side effect. Radiopaque contrast dyes, used in some radiologic procedures, may also result in acute tubular necrosis as a rare complication from contrast dye use. Acronym: ATN (13 Nov 1997) |
| avascular necrosis | <radiology> Aetiology (PLASTIC RAGS): P pancreatitis, L lupus, A alcohol, S steroids, T trauma, I idiopathic, infection, C caisson disease, collagen vascular disease, R radiation, rheumatoid arthritis, A amyloid, G Gaucher disease, S sickle cell disease findings: sclerosis, crescent sign, collapse (e.g., of femoral head) see also: staging (12 Dec 1998) |
| avascular necrosis staging | <radiology> Stage CT/X-ray bone scan I - cold/hot spot II sclerotic focus with osteopenic ring III crescent sign (subchondral lucency) IV articular collapse flattening of femoral head sensitivity 86% 78% specificity 79% 75% see also: avascular necrosis (AVN) (12 Dec 1998) |
| bridging hepatic necrosis | Area of liver necrosis which bridges adjacent portal areas and central veins; subsequent post-necrotic collapse and fibrosis is likely to result in cirrhosis. (05 Mar 2000) |
| p60 tumour necrosis factor receptor-associated kinase | <enzyme> Interacts with and causes phosphorylation of the cytoplasmic domain of the tnf receptor Registry number: EC 2.7.10.- Synonym: p60 tnf receptor-associated kinase, p60-trak (26 Jun 1999) |
| papillary necrosis | <radiology> Mnemonic: POST CARD, P pyelonephritis, O obstruction, S sickle cell disease, T TB, C cirrhosis (EtOH), A analgesics (phenacetin and aspirin), R renal vein thrombosis, D diabetes (12 Dec 1998) |
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |