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area under the curve In pharmacokinetics, a mathematical calculation to evaluate the body's total exposure over time to a given drug. In a graph plotting how drug concentration in the blood changes after dosing, the drug concentration variable lies on the y-axis and time lies on the x-axis. The area between a drug concentration curve and the x-axis for a designated time interval is the AUC. AUCs are used as a guide for dosing schedules and to compare the different drugs' availability in the body.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
area under the curve a measure of drug concentration.
Ãâó: www.aegis.com/pubs/beta/1999/be990414.html
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