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arbaprostil <chemical> (5z,11 alpha,13e,15r)-11,15-dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic acid. A synthetic prostaglandin e analog that protects the gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumours.
Pharmacological action: anti-ulcer agents.
Chemical name: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (5Z,11alpha,13E,15R)-
(12 Dec 1998)
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