| arachidonate 15-lipoxygenase |
[EC 1.13.11.33] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 15 position to form 15-hydroperoxyeicosatetraenoic acid (15-HPETE). The reaction occurs primarily in vascular endothelium and is the first step in the conversion of arachidonic acid to 15-hydroxyeicosatetraenoic acid (15-HETE) and to lipoxins.
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