| arachidonate 12-lipoxygenase |
[EC 1.13.11.31] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 12 position to form 12-hydroperoxyeicosatetraenoic acid (12-HPETE). The reaction occurs primarily in platelets and is the first step of the lipoxygenase pathway for conversion of arachidonic acid to the leukotriene 12-hydroxyeicosatetraenoic acid (12-HETE).
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