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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Apoptosis - »õâ One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
    Synonyms : Apoptosis, Extrinsic Pathway, Apoptosis, Intrinsic Pathway, Programmed Cell Death, Type I, Apoptoses, Extrinsic Pathway, Apoptoses, Intrinsic Pathway, Extrinsic Pathway Apoptoses, Extrinsic Pathway Apoptosis, Intrinsic Pathway Apoptoses
  • Apoptosis Inducing Factor - »õâ A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.
    Synonyms : AIF Apoptosis Regulatory Protein, Apoptosis-Inducing Factor, Mitochondrial Apoptosis-Inducing Factor, Apoptosis-Inducing Factor, Mitochondrial, Mitochondrial Apoptosis Inducing Factor
  • Apoptosis Regulatory Proteins - »õâ A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.
    Synonyms : Apoptosis Inducing Proteins, Apoptosis Inhibiting Proteins, Death Factors (Apoptosis), Programmed Cell Death Proteins, Survival Factors (Apoptosis), Regulatory Proteins, Apoptosis
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 1
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